drugset / Trial / NCT01063205
NAC as a Potential Treatment for Methamphetamine Dependence
Phase 1
Completed
10 enrolled
Baylor College of Medicine
National Institute on Drug Abuse (NIDA) · collab
RandomizedParallel-groupQuadruple-blind
Summary
The purpose of this study is to determine the effects of treatment with NAC, compared to treatment with placebo, on cue- and methamphetamine (MA)-induced craving and MA subjective effects in non-treatment-seeking MA-dependent human volunteers. We also aim to determine the effects of treatment with NAC, compared to treatment with placebo, on the reinforcing effects of MA by measuring MA self-administration in non-treatment-seeking MA-dependent human volunteers.
Timeline
- Start
- 2010-03
- Primary completion
- 2011-07
- Completion
- 2011-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | N-acetylcysteine | Small molecule | 1800 mg | — |
| Comparator | N-acetylcysteine | Small molecule | 3600 mg | — |