drugset / Trial / NCT01063205

NAC as a Potential Treatment for Methamphetamine Dependence

NCT01063205

RandomizedParallel-groupQuadruple-blind

Summary

The purpose of this study is to determine the effects of treatment with NAC, compared to treatment with placebo, on cue- and methamphetamine (MA)-induced craving and MA subjective effects in non-treatment-seeking MA-dependent human volunteers. We also aim to determine the effects of treatment with NAC, compared to treatment with placebo, on the reinforcing effects of MA by measuring MA self-administration in non-treatment-seeking MA-dependent human volunteers.

Timeline

Start
2010-03
Primary completion
2011-07
Completion
2011-07

Drugs

EvaluationDrugModalityDoseRoute
Comparator N-acetylcysteine Small molecule 1800 mg
Comparator N-acetylcysteine Small molecule 3600 mg