drugset / Trial / NCT01063647
Dose-range Finding Treosulfan-based Conditioning
Non-randomizedParallel-groupOpen-labelTreatment
Summary
Evaluation of the safety and efficacy of 3 x 10, 3 x 12 or 3 x 14 g/m² Treosulfan resp., combined with 5 x 30 mg/m² fludarabine prior to allogeneic, hematopoietic stem cell transplantation of patients with hematological malignancies, but non-eligible to standard conditioning treatment.
Timeline
- Start
- 2001-11
- Primary completion
- 2005-06
- Completion
- 2006-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Treosulfan | Small molecule | 10 g | Intravenous |
| Subject | Treosulfan | Small molecule | 12 g | Intravenous |
| Subject | Treosulfan | Small molecule | 14 g | Intravenous |