drugset / Trial / NCT01064219

Intrauterine Human Chorionic Gonadotrophins (hCG) and Endometrial Treg Cells

NCT01064219

Completed 20 enrolled The Egyptian IVF-ET Center
RandomizedParallel-groupDouble-blindDiagnostic

Summary

Intrauterine injection of hCG around the time of implantation may increase endometrial Treg cells and improve implantation. It has been demonstrated that regulatory T cells expand during pregnancy. hCG was found to be secreted by the embryo immediately after fertilization and has chemoattractant properties to Treg cells.

Timeline

Start
2010-02
Primary completion
2010-12
Completion
2010-12

Drugs

EvaluationDrugModalityDoseRoute
Subject human chorionic gonadotropin Protein / enzyme biologic 100 iu Other

Indications