human chorionic gonadotropin
Protein / enzyme biologic targets LHCGR via activation
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | PREGNYL | — | 1976-10-20 | fda.gov ↗ |
Trials 55
| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 02 trials · 1 missed | ||||||
| Phase 0 | NCT02265861 | Jan 2010 → Jun 2012 | polycystic ovary syndrome | Nanjing University School of Medicine | Completed | No outcome recorded |
| Phase 0 | NCT01414673 | Apr 2009 → Jul 2011 | — | University Hospital Brussels | Completed | Missed primary |
| Phase 13 trials · 1 missed | ||||||
| Phase 1 | NCT06754332 | Apr 2025 → Apr 2028 expected | primary ovarian failure | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | Not yet recruiting | No outcome recorded |
| Phase 1 | NCT03735030 | Nov 2018 → Aug 2019 | infertility disorder | IBSA Institut Biochimique SA | Completed | Missed primary |
| Phase 1 | NCT03418896 | Jan 2018 → Oct 2022 | calcium metabolic disease, hypogonadism, kidney disorder | Martin Blomberg Jensen | Completed | No outcome recorded |
| Phase 1/24 trials · 1 met primary | ||||||
| Phase 1/2 | NCT05123040 | Jun 2023 → Feb 2026 | acute graft versus host disease | Masonic Cancer Center, University of Minnesota | Terminated | No outcome recorded Stop: Business |
| Phase 1/2 | NCT02525029 | Mar 2016 → May 2021 | acute graft versus host disease | Masonic Cancer Center, University of Minnesota | Completed | No outcome recorded |
| Phase 1/2 | NCT02427529 | May 2011 → Dec 2012 | — | Dr. Emma's Corporation | Completed | No outcome recorded |
| Phase 1/2 | NCT00839319 | Mar 2009 → Sep 2010 | — | University of Washington | Completed | Met primary |
| Phase 23 trials · 1 missed | ||||||
| Phase 2 | NCT02544191 | Dec 2015 → Dec 2017 | azoospermia | Jinling Hospital, China | Unknown | No outcome recorded |
| Phase 2 | NCT01239706 | Nov 2010 → Jun 2012 | traumatic brain injury | University of Calgary | Unknown | No outcome recorded |
| Phase 2 | NCT00938314 | Aug 2009 → Apr 2010 | ischemic stroke | Stem Cell Therapeutics Corp. | Terminated | Missed primary Stop: Enrollment |
| Phase 38 trials · 1 met primary · 1 missed | ||||||
| Phase 3 | NCT07216742 | Nov 2025 → Nov 2028 expected | infertility disorder | Granata Bio Corporation | Recruiting | No outcome recorded |
| Phase 3 | NCT05586802 | Mar 2023 → Apr 2027 expected | Klinefelter syndrome | Georgios Papadakis | Recruiting | No outcome recorded |
| Phase 3 | NCT02798653 | Nov 2015 → Nov 2019 | infertility disorder | Royan Institute | Unknown | No outcome recorded |
| Phase 3 | NCT02825108 | Jan 2015 → Dec 2018 | infertility disorder | Royan Institute | Completed | No outcome recorded |
| Phase 3 | NCT02355925 | Oct 2014 → Dec 2018 | infertility disorder | Royan Institute | Completed | Missed primary |
| Phase 3 | NCT02310919 | Sep 2014 → Jun 2018 | infertility disorder | University of California, San Francisco | Completed | Met primary |
| Phase 3 | NCT01507376 | Oct 2010 → Sep 2012 | — | Royan Institute | Completed | No outcome recorded |
| Phase 3 | NCT01081756 | Dec 2003 → Sep 2004 | female infertility | Merck KGaA, Darmstadt, Germany | Completed | No outcome recorded |
| Phase 418 trials · 2 met primary · 3 missed | ||||||
| Phase 4 | NCT05340010 | Jan 2020 → Jun 2022 | — | Alexandria University | Completed | Missed primary |
| Phase 4 | NCT03846544 | Oct 2019 → Sep 2021 | infertility disorder | CRG UZ Brussel | Completed | Missed primary |
| Phase 4 | NCT05638529 | May 2019 → Dec 2023 | female infertility, ovarian hyperstimulation syndrome | Mount Sinai Hospital, Canada | Unknown | No outcome recorded |
| Phase 4 | NCT03687606 | Oct 2018 → Oct 2024 | Kallmann syndrome, infertility disorder | Tongji Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT03115320 | Jan 2017 → Nov 2019 | infertility disorder | Tampere University Hospital | Terminated | No outcome recorded |
| Phase 4 | NCT02880280 | Aug 2016 → Aug 2017 | Kallmann syndrome | Beijing Children's Hospital | Unknown | No outcome recorded |
| Phase 4 | NCT02715336 | Oct 2015 → Sep 2020 | habitual spontaneous abortion, ovarian hyperstimulation syndrome, pregnancy disorder | Create Fertility Center | Unknown | No outcome recorded |
| Phase 4 | NCT01980680 | Dec 2014 → Sep 2019 | infertility disorder | Peter Humaidan | Completed | No outcome recorded |
| Phase 4 | NCT01786252 | Jan 2013 → Mar 2016 | infertility disorder | Michigan State University | Completed | Mixed |
| Phase 4 | NCT01529177 | Feb 2012 → Sep 2016 | male infertility | The Egyptian IVF-ET Center | Unknown | No outcome recorded |
| Phase 4 | NCT01768247 | Jan 2012 → Dec 2013 | — | University Hospital Brussels | Unknown | No outcome recorded |
| Phase 4 | NCT01030393 | Jan 2010 → Jan 2011 | infertility disorder | The Egyptian IVF-ET Center | Completed | Met primary |
| Phase 4 | NCT00844311 | Feb 2009 → Jun 2010 | infertility disorder | Rigshospitalet, Denmark | Completed | Met primary |
| Phase 4 | NCT02638285 | Jan → Aug 2009 | pregnancy disorder | Shiraz University of Medical Sciences | Completed | No outcome recorded |
| Phase 4 | NCT01601327 | Jan 2008 → Mar 2012 | hypogonadotropic hypogonadism | Gulhane School of Medicine | Completed | No outcome recorded |
| Phase 4 | NCT00750100 | Sep 2007 → Jan 2008 | infertility disorder | University Hospital Brussels | Completed | No outcome recorded |
| Phase 4 | NCT00415792 | Nov 2003 → Jul 2005 | infertility disorder | Eugonia | Unknown | No outcome recorded |
| Phase 4 | NCT00286364 | — | infertility disorder | Rigshospitalet, Denmark | Completed | Missed primary |
| Phase not applicable17 trials · 2 missed | ||||||
| — | NCT07633002 | Jul 2026 → Dec 2027 expected | obesity disorder | The Second Hospital of Shandong University | Not yet recruiting | No outcome recorded |
| — | NCT07608133 | Dec 2025 → Apr 2026 | — | Pakistan Air Force (PAF) Hospital Islamabad | Completed | No outcome recorded |
| — | NCT06142708 | Nov 2023 → Apr 2025 | — | Embryolab Fertility Clinic | Unknown | No outcome recorded |
| — | NCT05569577 | Jan 2021 → Dec 2025 overdue | rubeosis iridis | Fudan University | Recruiting | No outcome recorded |
| — | NCT04855383 | Jul 2020 → Aug 2022 | — | Royan Institute | Completed | No outcome recorded |
| — | NCT03682614 | Dec 2018 → Aug 2019 | infertility disorder | Reproductive & Genetic Hospital of CITIC-Xiangya | Completed | No outcome recorded |
| — | NCT03238807 | Jul 2018 → Oct 2020 | infertility disorder | Assiut University | Completed | Missed primary |
| — | NCT03445910 | Feb → Jun 2018 | infertility disorder | Ain Shams University | Completed | No outcome recorded |
| — | NCT02870855 | Jul 2017 → Jan 2018 | infertility disorder | Reproductive & Genetic Hospital of CITIC-Xiangya | Withdrawn | No outcome recorded |
| — | NCT03825445 | Apr 2016 → Jun 2017 | female infertility | Hue University of Medicine and Pharmacy | Completed | No outcome recorded |
| — | NCT01986374 | Jun 2013 → Dec 2015 | infertility disorder | Servy Massey Fertility Insititute | Completed | No outcome recorded |
| — | NCT01931384 | Jul 2012 → Dec 2015 | infertility disorder | The University of Hong Kong | Completed | Missed primary |
| — | NCT02788136 | Feb 2012 → Jul 2014 | Klinefelter syndrome, steroid inherited metabolic disorder | Azienda USL Modena | Completed | No outcome recorded |
| — | NCT01780610 | Jan 2012 → Jan 2015 | infertility disorder | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Unknown | No outcome recorded |
| — | NCT01064219 | Feb → Dec 2010 | infertility disorder | The Egyptian IVF-ET Center | Completed | No outcome recorded |
| — | NCT00646568 | Jun 2008 → Jan 2010 | infertility disorder | Hadassah Medical Organization | Completed | No outcome recorded |
| — | NCT00223860 | Jul 2001 → Dec 2007 | hypogonadism, spinal cord injury | US Department of Veterans Affairs | Completed | No outcome recorded |
| Comparator or background therapy64 trials | ||||||
| Phase 1 | NCT06367712 Comparator | Nov 2022 → Nov 2023 | polycystic ovary syndrome | Egymedicalpedia | Completed | No outcome recorded |
| Phase 1/2 | NCT00947713 Comparator | Aug 2009 → Aug 2010 | gonadal disorder | Royan Institute | Completed | No outcome recorded |
| Phase 1/2 | NCT00823121 Comparator | Aug 2008 → Feb 2009 | — | Yazd Research & Clinical Center for Infertility | Unknown | No outcome recorded |
| Phase 2 | NCT06904599 Comparator | Feb 2025 → Jan 2026 overdue | acute graft versus host disease | Hospital Universitario Dr. Jose E. Gonzalez | Recruiting | No outcome recorded |
| Phase 2 | NCT07635082 Comparator | Feb 2024 → Jun 2025 | polycystic ovary syndrome | Eman Basuni Ebrahim Mowad | Completed | No outcome recorded |
| Phase 2 | NCT04189133 Comparator | Jan 2022 → Jan 2025 | hypogonadotropic hypogonadism | University Hospital of Modena | Unknown | No outcome recorded |
| Phase 2 | NCT04850261 Comparator | May 2021 → Mar 2024 | infertility disorder | Insel Gruppe AG, University Hospital Bern | Withdrawn | No outcome recorded |
| Phase 2 | NCT01204840 Comparator | Sep 2010 → May 2015 | infertility disorder, ovarian dysfunction | Ottawa Fertility Centre | Completed | No outcome recorded |
| Phase 2 | NCT01232075 Comparator | Sep 2008 → Nov 2010 | infertility disorder | Cairo University | Completed | No outcome recorded |
| Phase 2 | NCT00398229 Comparator | Nov 2006 → May 2008 | female infertility | Hadassah Medical Organization | Completed | No outcome recorded |
| Phase 2 | NCT00844350 Comparator | Oct 2006 → Sep 2007 | ovarian disorder | Tabriz University | Completed | No outcome recorded |
| Phase 2 | NCT00702806 Background | Jul 2001 → Oct 2002 | infertility disorder | Organon and Co | Completed | No outcome recorded |
| Phase 2/3 | NCT04870502 Comparator | Apr 2019 → Jul 2020 | polycystic ovary syndrome | Saudi German Hospital - Madinah | Completed | No outcome recorded |
| Phase 3 | NCT06725004 Comparator | Jan → Dec 2023 | female infertility, polycystic ovary syndrome | Shakeela Ishrat | Completed | No outcome recorded |
| Phase 3 | NCT06486870 Background | Jan 2020 → Jan 2024 | polycystic ovary syndrome | Cairo University | Completed | No outcome recorded |
| Phase 3 | NCT04224818 Background | Jul 2018 → Aug 2019 | ovarian dysfunction | American University of Beirut Medical Center | Completed | No outcome recorded |
| Phase 3 | NCT02862782 Background | Sep 2016 → Sep 2019 | — | Tel-Aviv Sourasky Medical Center | Unknown | No outcome recorded |
| Phase 3 | NCT02264847 Comparator | Oct 2014 → Apr 2017 | anovulation | Cairo University | Unknown | No outcome recorded |
| Phase 3 | NCT02739516 Background | Jun 2014 → Aug 2015 | infertility disorder | Benha University | Completed | No outcome recorded |
| Phase 3 | NCT01709331 Background | Feb 2013 → Apr 2015 | hypogonadotropic hypogonadism | Organon and Co | Completed | Met primary |
| Phase 3 | NCT01653743 Comparator | Sep 2012 → Nov 2014 | anovulation, hypothalamic dysfunction, polycystic ovary syndrome | Merck KGaA, Darmstadt, Germany | Completed | No outcome recorded |
| Phase 3 | NCT00948805 Background | Jan → Dec 2009 | infertility disorder | University of Sao Paulo | Unknown | No outcome recorded |
| Phase 3 | NCT00954265 Comparator | Aug 2005 → Dec 2007 | Somatomedin, embryonic, perifoveal exudative vascular anomalous complex, pregnancy disorder | University Hospital Brussels | Unknown | No outcome recorded |
| Phase 3 | NCT01084265 Background | Feb 2004 → Dec 2005 | hypogonadism | Merck KGaA, Darmstadt, Germany | Completed | No outcome recorded |
| Phase 4 | NCT06684951 Comparator | Oct 2022 → Jan 2024 | female infertility | Omayma Ismail Khalaf | Completed | No outcome recorded |
| Phase 4 | NCT04997525 Comparator | Apr 2021 → May 2024 | infertility disorder | Copenhagen University Hospital at Herlev | Completed | No outcome recorded |
| Phase 4 | NCT04724486 Background | Aug 2020 → Mar 2022 | infertility disorder | Damascus University | Completed | No outcome recorded |
| Phase 4 | NCT04727684 Background | Aug 2020 → Feb 2022 | infertility disorder, polycystic ovary syndrome | Damascus University | Completed | No outcome recorded |
| Phase 4 | NCT04724343 Background | Dec 2019 → Jan 2022 | infertility disorder | Damascus University | Completed | No outcome recorded |
| Phase 4 | NCT04727671 Background | Dec 2019 → Aug 2021 | infertility disorder, polycystic ovary syndrome | Damascus University | Completed | No outcome recorded |
| Phase 4 | NCT03784404 Comparator | Dec 2018 → Dec 2019 | ovarian endometriosis | Cairo University | Unknown | No outcome recorded |
| Phase 4 | NCT04008966 Comparator | Jul 2016 → Jun 2019 | — | Cairo University | Completed | No outcome recorded |
| Phase 4 | NCT02436226 Comparator | Mar 2016 → Jan 2023 | female infertility, polycystic ovary syndrome | Mohamed Sayed Abdelhafez | Completed | No outcome recorded |
| Phase 4 | NCT02703584 Background | Mar 2016 → Sep 2018 | infertility disorder | Mount Sinai Hospital, Canada | Completed | No outcome recorded |
| Phase 4 | NCT02397551 Comparator | Mar 2015 → Jan 2018 | infertility disorder | Cairo University | Completed | No outcome recorded |
| Phase 4 | NCT02288143 Background | Jan → Mar 2015 | infertility disorder | University of Sao Paulo | Completed | No outcome recorded |
| Phase 4 | NCT02048891 Comparator | Oct 2014 → Jan 2015 | infertility disorder | Rambam Health Care Campus | Completed | No outcome recorded |
| Phase 4 | NCT04605107 Comparator | Aug 2013 → Jan 2015 | female infertility | Genuine Research Center, Egypt | Completed | No outcome recorded |
| Phase 4 | NCT01815138 Comparator | Mar 2013 → Dec 2015 | ovarian hyperstimulation syndrome | UConn Health | Completed | No outcome recorded |
| Phase 4 | NCT01607203 Comparator | Nov 2011 → Dec 2013 | infertility disorder | AZ Jan Palfijn Gent | Completed | No outcome recorded |
| Phase 4 | NCT01888744 Comparator | Sep 2010 → Jun 2013 | infertility disorder | University Hospital Brussels | Completed | No outcome recorded |
| Phase 4 | NCT02310074 Comparator | Jan 2010 → Jun 2014 | hypogonadotropic hypogonadism | Shanghai Jiao Tong University School of Medicine | Unknown | No outcome recorded |
| Phase 4 | NCT01403532 Comparator | Sep 2009 → Dec 2012 | Kallmann syndrome | Shanghai Jiao Tong University School of Medicine | Completed | Met primary |
| Phase 4 | NCT00627406 Comparator | Jan 2009 → Dec 2011 | ovarian hyperstimulation syndrome | Regionshospitalet Viborg, Skive | Completed | Missed primary |
| Phase 4 | NCT00870025 Comparator | Oct 2008 → Sep 2010 | ovarian disorder | IVI Madrid | Completed | No outcome recorded |
| Phase 4 | NCT01365936 Comparator | Jan → Jun 2008 | polycystic ovary syndrome | Zekai Tahir Burak Women's Health Research and Education Hospital | Completed | No outcome recorded |
| Phase 4 | NCT00439829 Background | Feb 2007 → May 2010 | female infertility | University of Saskatchewan | Completed | No outcome recorded |
| Phase 4 | NCT00953628 Comparator | Aug 2005 → Dec 2006 | infertility disorder | University Hospital Brussels | Completed | No outcome recorded |
| — | NCT07861399 Comparator | Sep 2026 → Aug 2028 expected | — | Al-Azhar University | Recruiting | No outcome recorded |
| — | NCT05828966 Comparator | Feb → May 2023 | — | Shaheed Zulfiqar Ali Bhutto Medical University | Completed | No outcome recorded |
| — | NCT05874518 Comparator | Dec 2021 → Apr 2022 | ovarian dysfunction | Liuzhou Maternity and Child Healthcare Hospital | Completed | No outcome recorded |
| — | NCT05112692 Comparator | Nov 2021 → Nov 2023 | polycystic ovary syndrome | Mansoura University | Unknown | No outcome recorded |
| — | NCT03904355 Comparator | May 2019 → Apr 2022 | female infertility | Cairo University | Unknown | No outcome recorded |
| — | NCT03904368 Comparator | Apr 2019 → Dec 2020 | uterus interstitial leiomyoma | Cairo University | Unknown | No outcome recorded |
| — | NCT03398993 Comparator | Jan → Dec 2018 | infertility disorder | Cairo University | Unknown | No outcome recorded |
| — | NCT03307720 Comparator | Dec 2017 → Feb 2018 | female infertility, ovarian disorder | Ginegorama S.L. | Unknown | No outcome recorded |
| — | NCT02940535 Background | Dec 2016 → Dec 2019 | anovulation, female infertility | Navy General Hospital, Beijing | Unknown | No outcome recorded |
| — | NCT02827656 Comparator | Aug 2016 → Aug 2017 | infertility disorder | Meir Medical Center | Unknown | No outcome recorded |
| — | NCT02775877 Comparator | May 2016 → Jun 2019 | female infertility | Navy General Hospital, Beijing | Unknown | No outcome recorded |
| — | NCT02397642 Comparator | Mar 2015 → Jan 2018 | infertility disorder | Cairo University | Completed | No outcome recorded |
| — | NCT03457233 Comparator | Jan 2015 → Mar 2018 | — | Cairo University | Unknown | No outcome recorded |
| — | NCT02293668 Comparator | Nov 2014 → Aug 2015 | infertility disorder | Istanbul University | Completed | No outcome recorded |
| — | NCT02148393 Comparator | May 2014 → Feb 2017 | infertility disorder, ovarian hyperstimulation syndrome | University Hospital Brussels | Completed | No outcome recorded |
| — | NCT03484611 Comparator | Jan 2013 → Apr 2018 | — | Cairo University | Unknown | No outcome recorded |
Evidence & citations 25 cited values
Every value below carries the sentence it was read from. 133 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Human Chorionic Gonadotropin | “Although GnRHa triggering was shown to be as effective as human chorionic gonadotropin (hCG) at inducing oocyte maturation more than 20 years ago, its use to trigger ovulation...” NCT02715336 ↗87“OBJECTIVE: To assess if triggering with 1,500 IU of human chorionic gonadotropin (hCG) with 450 IU of follicle-stimulating hormone (FSH) induces noninferior oocyte competence...” PMID 35705380 ↗ Jun 2022 “When follicles achieve a diameter greater than 10 mm they start expressing luteinising hormone (LH) receptors. At this point, FSH might be replaced by low-dose human chorionic...” PMID 23543584 ↗ Mar 2013 “The purpose of this trial is to study whether addition of different doses of human chorionic gonadotropins during controlled ovarian stimulation for patients undergoing IVF...” NCT00844311 ↗ “When at least 3 follicles reached 18 mm, ovulation was triggered using Human Chorionic Gonadotropin 10000 IU (Epifasi 10000 IU; Eipico, Tenth of Ramadan, Egypt) IM and ovum...” NCT03784404 ↗ “In this clinical trial study, 52 patients with PCOS and 8 control cases were stimulated with human chorionic gonadotropin (HCG) on the 4(th) to 7(th) day of the patients'...” PMID 25780518 ↗ Feb 2015 “Luteal phase support (LPS) is one of the indispensable interventions in ART treatments for IHH patients, which includes progestin, estrogen, human chorionic gonadotropin (hCG),...” NCT05569577 ↗ “Human chorionic gonadotropin (HCG) hormone will replace the naturally surging luteinizing hormone at mid-cycle, subsequently, will lead to full maturation of oocytes resulting...” NCT06367712 ↗ “This randomized double blinded clinical trial is conducted to evaluate the effect of intrauterine injection of human chorionic gonadotropin (hCG) before frozen embryo transfer (ET).” NCT02825108 ↗ “OBJECTIVE: To characterize corpora lutea (CL) function after gonadotropin-releasing hormone agonist (GnRHa) trigger with the use of adjuvant human chorionic gonadotropin (hCG).” PMID 31227286 ↗ Jun 2019 “Then human menopausal gonadotropin (hMG) and human chorionic gonadotropin (hCG) were injected to stimulate them to ameliorate the ability of testicular spermatogenesis.” PMID 30243299 ↗ Sep 2018 |
| Known as | Chorimon | “Human chorionic gonadotropin Chorimon” NCT03457233 ↗ |
| Known as | Choriomon | “40 μL of tissue culture medium (G.2plus ref. 10132, Vitrolife) containing either 500 IU of hCG (Choriomon®, IBSA SA, Switzerland) is injected intrauterine, approximately 7...” NCT02825108 ↗7“Oxytocin (OXYTIP; manufactured by IPDIC, Rasht, Iran), 5 IU and hCG (Choriomon; manufactured by IBSA Institute Biochimique SA, CH-6903 Lugano), 5000 IU were also administrated...” NCT00844350 ↗ “Choriomon®, a highly purified hCG formulation, is approved in many European and extra-European countries for the induction of ovulation after stimulation of follicular development.” PMID 35137345 ↗ Feb 2022 “Intramuscular injection of 1,500 IU of hCG (Choriomon®; IBSA) on the embryos transfer (ET) day, as well as 4 days after the embryos transfer for luteal support” NCT02798653 ↗ “When one follicle reached a size of \> =18 mm a single dose of 10,000 IU human chorionic gonadotrophin (hCG, Pregnyl, Epifasi, Choriomon) is given.” NCT06486870 ↗ “Clomid 50 mg per day will be administered orally and human chorionic gonadotrophin ( choriomon ) 5000 IU will be administered IM once per week.” NCT01529177 ↗ “containing either 500 IU of hCG (Choriomon®, IBSA SA, Switzerland) is injected intrauterine” NCT02355925 ↗ “human Chorionic Gonadotropin (Choriomon 10,000 IU subcutaneous once)” NCT04224818 ↗ |
| Known as | Chorionic gonadotrophin | “When the diameter of follicles reaches 18mm, Chorionic gonadotrophin is given at 5000u (Lizhu Group Lizhu Pharmaceutical Factory, Chinese medicine H44020668, 5000u per branch),...” NCT05874518 ↗ |
| Known as | Chorionic Gonadotropin, Alpha | ClinicalTrials.gov intervention name — accepted as the source's own label NCT04997525 ↗ |
| Known as | EPICO | “a total of 10,000 IU of hCG (Epifasi, EPICO) was administered to those in whom at least one ovarian follicle was ≥18 mm in size.” NCT02739516 ↗ |
| Known as | Epifasi | “When at least 3 follicles reached 18 mm, ovulation was triggered using Human Chorionic Gonadotropin 10000 IU (Epifasi 10000 IU; Eipico, Tenth of Ramadan, Egypt) IM and ovum...” NCT03784404 ↗3“When one follicle reached a size of \> =18 mm a single dose of 10,000 IU human chorionic gonadotrophin (hCG, Pregnyl, Epifasi, Choriomon) is given.” NCT06486870 ↗ “a total of 10,000 IU of hCG (Epifasi, EPICO) was administered to those in whom at least one ovarian follicle was ≥18 mm in size.” NCT02739516 ↗ “Epifasi: Human chorionic gonadotrophin” NCT04605107 ↗ |
| Known as | Gonasi HP | “The comparator is Gonasi HP.” NCT04189133 ↗ |
| Known as | hCG | “The present study tested whether short-term androgen priming by aromatase inhibitor and human chorionic gonadotrophin (hCG) before controlled ovarian stimulation (COS)...” PMID 18487212 ↗ May 200864“This randomised controlled trial (RCT) further explored whether low-dose hCG can be used clinically to replace recombinant FSH (rFSH) during the late follicular phase in a...” PMID 19617207 ↗ Jul 2009 “This randomized double blinded clinical trial is conducted to evaluate the effect of intrauterine injection of human chorionic gonadotropin (hCG) before frozen embryo transfer (ET).” NCT02825108 ↗ “The study population in frozen embryo transfer cycles receive three doses of human chorionic gonadotropin (HCG) to recognize the effectiveness of HCG on pregnancy outcomes” NCT04855383 ↗ “Then human menopausal gonadotropin (hMG) and human chorionic gonadotropin (hCG) were injected to stimulate them to ameliorate the ability of testicular spermatogenesis.” PMID 30243299 ↗ Sep 2018 “Ovulation will be triggered by the administration of 10,000 IU of Human Chorionic Gonadotropin (hCG) when at least three follicles become more than 16-17 mm.” NCT04727671 ↗ “Routinely, human chorionic gonadotropin (hCG) is used for that purpose given its similarity to the natural hormone that does this job in a natural cycle” NCT02048891 ↗ “When at least one dominant follicle reaches a mean diameter of 18-20 mm, human chorionic gonadotropin (hCG) will be administered to trigger ovulation.” NCT07635082 ↗ “Human Chorionic Gonadotropin (hCG) Priming Prior to Controlled Ovarian Hyperstimulation (COH) in Poor Responder In Vitro Fertilization (IVF) Patients” NCT00870025 ↗ “When one follicle reached a size of \> =18 mm a single dose of 10,000 IU human chorionic gonadotrophin (hCG, Pregnyl, Epifasi, Choriomon) is given.” NCT06486870 ↗ “including progesterone alone, human chorionic gonadotropin (hCG) alone, and the combination of progesterone with hCG, in these patients.” PMID 39827385 ↗ Jan 2025 |
| Known as | HMG | ClinicalTrials.gov intervention name — accepted as the source's own label NCT02775877 ↗ |
| Known as | human chorionic gonadotrophin | “The present study tested whether short-term androgen priming by aromatase inhibitor and human chorionic gonadotrophin (hCG) before controlled ovarian stimulation (COS)...” PMID 18487212 ↗ May 200811“When one follicle reached a size of \> =18 mm a single dose of 10,000 IU human chorionic gonadotrophin (hCG, Pregnyl, Epifasi, Choriomon) is given.” NCT06486870 ↗ “Clomid 50 mg per day will be administered orally and human chorionic gonadotrophin ( choriomon ) 5000 IU will be administered IM once per week.” NCT01529177 ↗ “administration of human chorionic gonadotrophin (HCG) in patients undergoing intrauterine insemination (IUI) in natural cycles” PMID 22796236 ↗ May 2012 |
| Known as | Human Chorionic Gonadotropin(hCG) | “Human Chorionic Gonadotropin(hCG)” NCT02880280 ↗ |
| Known as | Human hCG | “Human hCG 10'000 IU” NCT03735030 ↗ |
| Known as | human menopausal gonadotropin | “Control group (CC/hMG) will receive the 100 mg CC on days 3 to 7 of that cycle but will receive 150 mg human menopausal gonadotropin (HMG) during days of 7, 8, and 9.” NCT00947713 ↗4“human menopausal gonadotropin (hMG) 225IU/day will be initiated on the second or third day of spontaneous menstruation” NCT02293668 ↗ “BACKGROUND: We aimed to compare human menopausal gonadotropin (hMG) and” PMID 24520446 ↗ Mar 2013 “Human Menopausal Gonadotropin, daily subcutaneous injection” NCT07216742 ↗ “Letrozole and human menopausal gonadotropin (HMG)” NCT02775877 ↗ |
| Known as | Menogon | “stimulation with hMG (Menogon; Ferring Pharmaceuticals. Istanbul) or rFSH (Gonal-F; Serono Istanbul).” NCT01365936 ↗ |
| Known as | Ovitrelle | “Injection of hCG - Human Chorionic Gonadotropin (Ovitrelle 250 mcg mcg - Merck Serono)” NCT02862782 ↗1“s.c. human chorionic gonadotropin (Ovitrelle)” NCT00398229 ↗ |
| Known as | Pregnyl | “After 2 months from the first Goserelin injection, all subjects were treated with hCG (Pregnyl, N.V. Organon Oss,Holland ) at a dose of 2000 IU once a week for 3 months.” NCT02544191 ↗17“When one follicle reached a size of \> =18 mm a single dose of 10,000 IU human chorionic gonadotrophin (hCG, Pregnyl, Epifasi, Choriomon) is given.” NCT06486870 ↗ “Human chorionic gonadotropin (Pregnyl; N.V. Organon, Oss, Holland) ( 10.000 IU/I.M ) is administered to trigger ovulation” NCT01232075 ↗ “Human chorionic gonadotropin (Pregnyl, 5000IU) is used in the medication group to confirme the ovulation.” NCT03115320 ↗ “hCG (Pregnyl 5000IU) for ovulation trigger after ovarian stimulation for IUI.” NCT03825445 ↗ “Human chorionic gonadotropin (hCG) (Pregnyl 5000 IU)” NCT01601327 ↗ “Agonist trigger Buserelin 0,5 mg and Pregnyl (hCG)” NCT01980680 ↗ “s.c. human chorionic gonadotropin (Pregnyl)” NCT00646568 ↗ “Pregnyl: Human chorionic gonadotrophin” NCT04605107 ↗ “Pregnyl, hCG, 5000 IU times one im.” NCT03418896 ↗ |
| Known as | rhCG | “When the follicle reached ≥18mm and estradiol reached ≥150pg/ml, recombinant human chorionic gonadotropin (rhCG) 250ug and triptorelin 0.1mg were co-administered to trigger ovulation.” NCT06754332 ↗ |
| Known as | u-hCG | “urinary human chorionic gonadotropin (u-hCG) 10,000 IU self-injected to complete final maturation of oocytes.” NCT01204840 ↗1“single dose of 5,000 IU u-hCG intramuscularly” NCT01653743 ↗ |
| Known as | uhCG/EGF | “Human Chorionic Gonadotropin (uhCG/EGF)” NCT05123040 ↗ |
| Known as | urinary hCG | “Urinary hCG (10,000 IU) injection s.c. or i.m.” NCT01081756 ↗ |
| Action | Activate | “hCG was shown to up-regulate gene expression during the differentiation of human endometrial stromal cells into decidua.” NCT00398229 ↗ |
| Modality | Protein / enzyme biologic | “urinary hCG” NCT01081756 ↗ |
| Route | Subcutaneous | “S.C. Ovitrelle 250 mcg once” NCT00398229 ↗ |
| Target | LHCGR | “Luteinizing hormone (LH) and human chorionic gonadotropin (hCG) are agonists for the luteinizing hormone receptor (LHCGR) which regulates male reproductive function.” PMID 33809538 ↗ Mar 2021 |