A Study of Human Chorionic Gonadotrophin as Luteal Phase Support in Frozen Embryo Transfer

Summary

A randomised trial on the use of luteal phase support in frozen-thawed embryo transfer cycles. The hypothesis of the study is that the use of luteal phase support with human chorionic gonadotrophin would increase the pregnancy rate in frozen-thawed embryo transfer cycles.

Timeline

Start

2012-07

Primary completion

2015-12

Completion

2015-12

Outcome

Missed primary endpoint

paper The use of hCG in natural cycle FET did not improve the ongoing pregnancy rate. PMID 28333292 ↗

Publications

• Lee VCY, Li RHW, Yeung WSB, Pak Chung HO, Ng EHY. A randomized double-blinded controlled trial of hCG as luteal phase support in natural cycle frozen embryo transfer. Hum Reprod. 2017 May 1;32(5):1130-1137. doi: 10.1093/humrep/dex049.

Drugs

Indications