drugset / Trial / NCT01980680
The Exogenous Progesterone Free Luteal Phase After GnRHa Trigger - a Pilot Study in Normo-responder IVF Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
After hCG trigger a large amount of exogenous progesterone is used for luteal phase support in many countries until 10th week of gestation. Instead we suggest the use of two small doses of hCG after the trigger during the early luteal phase after GnRHa trigger, promoting the endogenous progesterone production from the corpora lutea (CL).
Timeline
- Start
- 2014-12
- Primary completion
- 2019-09
- Completion
- 2020-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Estradiol | Other / unclassified | — | — |
| Comparator | Progesterone | Other / unclassified | — | — |
| Subject | human chorionic gonadotropin | Protein / enzyme biologic | — | — |