drugset / Trial / NCT01980680

The Exogenous Progesterone Free Luteal Phase After GnRHa Trigger - a Pilot Study in Normo-responder IVF Patients

NCT01980680

Phase 4 Completed 50 enrolled Peter Humaidan
RandomizedParallel-groupOpen-labelTreatment

Summary

After hCG trigger a large amount of exogenous progesterone is used for luteal phase support in many countries until 10th week of gestation. Instead we suggest the use of two small doses of hCG after the trigger during the early luteal phase after GnRHa trigger, promoting the endogenous progesterone production from the corpora lutea (CL).

Timeline

Start
2014-12
Primary completion
2019-09
Completion
2020-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Estradiol Other / unclassified
Comparator Progesterone Other / unclassified
Subject human chorionic gonadotropin Protein / enzyme biologic

Indications