Comparing the Efficacy of Urinary and Recombinant Human Chorionic Gonadotropin (hCG) on Oocyte Maturity

Phase 3 Completed 180 enrolled Royan Institute

RandomizedParallel-groupOpen-labelTreatment

Summary

This study is a prospective randomized clinical trial to compare the efficacy of the urinary and recombinant hCG on oocyte quality for ovulation induction in women undergoing IVF/ICSI.

Timeline

Start: 2010-10
Primary completion: 2012-09
Completion: 2013-06

Publications

Madani T, Mohammadi Yeganeh L, Ezabadi Z, Hasani F, Chehrazi M. Comparing the efficacy of urinary and recombinant hCG on oocyte/follicle ratio to trigger ovulation in women undergoing intracytoplasmic sperm injection cycles: a randomized controlled trial. J Assist Reprod Genet. 2013 Feb;30(2):239-45. doi: 10.1007/s10815-012-9919-3. Epub 2012 Dec 29.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	human chorionic gonadotropin	Protein / enzyme biologic	10000 iu	—
Subject	recombinant HCG	Protein / enzyme biologic	250 ug	—
Subject	recombinant HCG	Protein / enzyme biologic	500 ug	—

Indications

No indication recorded.