drugset / Trial / NCT01066572
Paramedic Initiated Lisinopril For Acute Stroke Treatment
Phase 1
Completed
14 enrolled
Newcastle-upon-Tyne Hospitals NHS Trust
North East Ambulance Service NHS Foundation Trust · collabNorthumbria Healthcare NHS Foundation Trust · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study aims to investigate the use of lisinopril to lower blood pressure in stroke patients, pre-hospital, by research-trained paramedics.
Timeline
- Start
- 2010-10
- Primary completion
- 2011-12
- Completion
- 2011-12
Publications
- Shaw L, Price C, McLure S, Howel D, McColl E, Younger P, Ford GA. Paramedic Initiated Lisinopril For Acute Stroke Treatment (PIL-FAST): results from the pilot randomised controlled trial. Emerg Med J. 2014 Dec;31(12):994-9. doi: 10.1136/emermed-2013-202536. Epub 2013 Sep 27.
- Shaw L, Price C, McLure S, Howel D, McColl E, Ford GA. Paramedic Initiated Lisinopril For Acute Stroke Treatment (PIL-FAST): study protocol for a pilot randomised controlled trial. Trials. 2011 Jun 15;12:152. doi: 10.1186/1745-6215-12-152.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LISINOPRIL ANHYDROUS | Small molecule | 5 mg | Oral |
| Subject | LISINOPRIL ANHYDROUS | Small molecule | 10 mg | Oral |