drugset / Trial / NCT01075321

Everolimus and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma

NCT01075321

Phase 1/2 Completed 58 enrolled Mayo Clinic
NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Everolimus may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Lenalidomide may stop the growth of cancer cells by blocking blood flow to the cancer. Giving everolimus together with lenalidomide may be an effective treatment for lymphoma. PURPOSE: This phase I/II trial is studying the side effects and best dose of giving everolimus and lenalidomide together and to see how well they work in treating patients with relapsed or refractory non-Hodgkin or Hodgkin lymphoma.

Timeline

Start
2011-01-10
Primary completion
2015-02-28
Completion
2020-02-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Everolimus Small molecule Oral
Subject Lenalidomide Other / unclassified