drugset / Trial / NCT01078974
Pomalidomide, Dexamethasone and Rituximab in Waldenstrom's Macroglobulinemia
NaSingle-groupOpen-labelTreatment
Summary
Pomalidomide is a newly discovered drug that may stop cancer cells from growing abnormally. Pomalidomide may also stimulate the immune system to fight the cancer cells and possibly improve the effectiveness of dexamethasone and rituximab to fight the Waldenstrom's Macroglobulinemia (WM) cancer cells. This drug have been used in multiple myeloma and information from these other research studies suggests that Pomalidomide may help to reduce or prevent the growth of cancer cells.
Timeline
- Start
- 2010-05
- Primary completion
- 2015-09
- Completion
- 2016-03
Outcome
Outcome not reported
Stopped: “Safety concerns (IgM Flare)”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pomalidomide | Other / unclassified | — | Oral |
| Background | Dexamethasone | Small molecule | — | Intravenous |
| Background | Rituximab | Monoclonal antibody | — | Intravenous |