drugset / Trial / NCT01080651
Influence of Drug-drug Interactions on the Pharmacokinetics (PK) of Voriconazole
Non-randomizedParallel-groupOpen-label
Summary
To evaluate the drug-drug interaction between rifampicin and voriconazole according to CYP2C19 genotype quantitatively following a single oral administration of 200 mg voriconazole
Timeline
- Start
- 2008-12
- Primary completion
- 2009-03
- Completion
- 2009-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Rifampin | Small molecule | 600 mg | Oral |
| Comparator | Voriconazole | Small molecule | 200 mg | Oral |