drugset / Trial / NCT01083667
SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS)
Phase 1/2
Completed
32 enrolled
Weill Medical College of Cornell University
Muscular Dystrophy Association · collab
NaSingle-groupOpen-labelTreatment
Summary
The objective of this study will be to evaluate the safety, tolerability and effect on SOD1 levels by pyrimethamine in patients with familial amyotrophic lateral sclerosis.
Timeline
- Start
- 2009-11
- Primary completion
- 2014-12
- Completion
- 2016-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | pyrimethamine | Small molecule | — | — |