drugset / Trial / NCT01088243

Targeting Oxidative Stress in Chronic Beryllium Disease

NCT01088243

Phase 1/2 Completed 18 enrolled National Jewish Health
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to understand if a drug called mesalamine helps to control inflammation associated with chronic beryllium disease (CBD). We hypothesize that in CBD subjects treated with prednisone, mesalamine treatment will enhance the immunosuppressive effects of prednisone, and thus reduce the immune response to beryllium.

Timeline

Start
2010-03
Primary completion
2015-03
Completion
2015-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Mesalamine Small molecule 500 mg