drugset / Trial / NCT01090128

Study of Neoadjuvant Chemotherapy With Nanoparticle Albumin Bound Paclitaxel, Doxorubicin and Cyclophosphamide (NAC) in Patients With Stages II-III Breast Cancer

NCT01090128 ↗

Phase 1 Terminated 27 enrolled University of Utah Celgene Corporation · collab
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this clinical trial is to test whether treatment of patients with breast cancer with the combination of Abraxane (nab-paclitaxel), Adriamycin (doxorubicin), and Cyclophosphamide prior to surgery is safe and results in good tumor response. Up to 24 patients may be enrolled in this study at the Mitchell Cancer Institute. All patients enrolling in this study will receive treatment with the combination of Abraxane, Adriamycin, and Cyclophosphamide.

Timeline

Start
2008-09
Primary completion
2017-03-24
Completion
2017-03-24

Outcome

Outcome not reported

Stopped: “Drug Manufacturer withdrew support for studies not in metastatic breast cancer”

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclophosphamide Other / unclassified 500 mg/m2 —
Subject Doxorubicin Other / unclassified 50 mg/m2 —
Subject nanoparticle albumin-bound paclitaxel Unknown 100 mg/m2 Intravenous

Indications