drugset / Trial / NCT01090323

Evaluation of the Safety, Tolerability, Pharmacokinetics (PK) and Effects on Liver Iron Concentration of ICL670 Relative to Deferoxamine(DFO).

NCT01090323

Phase 2 Completed 185 enrolled Novartis Pharmaceuticals
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The safety, tolerability, effects on liver iron concentration and pharmacokinetics of ICL670 is studied in sickle cell disease patients with transfusional hemosiderosis.

Timeline

Start
2004-07
Primary completion
2009-07
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Deferasirox Unknown 5 mg/kg Oral
Subject Deferasirox Unknown 40 mg/kg Oral

Indications