Pre-operative Preparation Using 2% Chlorhexidine Cloth For Shoulder Surgery

Summary

We intend to determine how effective the use of a 2% Chlorhexidine Cloth is in terms of eliminating the bacterial load on patients undergoing shoulder surgery. We will be comparing the Chlorhexidine Cloths with a control group which will be performing an ordinary shower prior to surgery. At this time, it is standard of care to only take an ordinary shower the evening prior, and the morning of surgery.

Timeline

Start

2010-01

Primary completion

2010-08

Completion

2010-10

Outcome

Met primary endpoint

paper In the treatment group vs the control group, the overall positive culture rate was 66% vs 94% (P = .0008) PMID 21612945 ↗

paper The use of the 2% chlorhexidine cloth was effective at decreasing overall bacterial culture rates before shoulder surgery PMID 21612945 ↗

Publications

• Murray MR, Saltzman MD, Gryzlo SM, Terry MA, Woodward CC, Nuber GW. Efficacy of preoperative home use of 2% chlorhexidine gluconate cloth before shoulder surgery. J Shoulder Elbow Surg. 2011 Sep;20(6):928-33. doi: 10.1016/j.jse.2011.02.018. Epub 2011 May 25.
• Saltzman MD, Nuber GW, Gryzlo SM, Marecek GS, Koh JL. Efficacy of surgical preparation solutions in shoulder surgery. J Bone Joint Surg Am. 2009 Aug;91(8):1949-53. doi: 10.2106/JBJS.H.00768.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Chlorhexidine gluconate	Other / unclassified	2 %	Other

Indications

No indication recorded.