drugset / Trial / NCT01090518

Cortisol Augmentation of a Psychological Treatment in Warfighters With Post Traumatic Stress Disorder (PTSD)

NCT01090518

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study seeks to examine the efficacy of hydrocortisone administration in the augmentation of the therapeutic effects of Prolonged Exposure (PE) therapy, an empirically tested treatment shown to be effective in the the treatment of posttraumatic stress disorder (PTSD). The augmentation builds on both the translation of neuroscience findings demonstrating the effects of glucocorticoids (GCs) on learning, and on empirical clinical findings from other investigators demonstrating beneficial effects of GCs in reducing traumatic memories in trauma-exposed persons.

Timeline

Start
2010-02
Primary completion
2013-11
Completion

Drugs

EvaluationDrugModalityDoseRoute
Comparator Hydrocortisone Other / unclassified 30 mg