Ondansetron Plus Dexamethasone With or Without Metoclopramide as Antiemetic Prophylaxis After Receiving Cisplatin

Summary

The objective of this study is to assess the efficacy and tolerability of metoclopramide added to standard antiemetic regimen for prophylaxis of cisplatin-induced emesis.

Timeline

Start

2009-04

Primary completion

2010-06

Completion

2010-10

Outcome

Missed primary endpoint

registry analysis (superiority or other test); Metoclopramide vs Placebo; p = 0.41; Chi-squared; note: No adjustment. NCT01093690 ↗

Drugs

Indications