drugset / Trial / NCT01094496

A Study of the CDX-1307 Vaccine Regimen in Patients With Newly Diagnosed Muscle-Invasive Bladder Cancer (The "N-ABLE" Study)

NCT01094496 ↗

Phase 2 Terminated 3 enrolled Celldex Therapeutics
NaSingle-groupOpen-labelTreatment

Summary

The major purpose of this study is to examine the anti-tumor activity of the CDX-1307 vaccine regimen when it is given before and after bladder cancer surgery. The study will also provide information about the safety of the vaccine regimen when given in combination with chemotherapy, and how it affects the immune systems.

Timeline

Start
2010-04
Primary completion
2011-07
Completion
2011-07

Outcome

Outcome not reported

Stopped (Enrollment): “Portfolio prioritization due to slow enrollment”

Drugs

EvaluationDrugModalityDoseRoute
Subject CDX-1307 Vaccine — —
Subject GM-CSF Protein / enzyme biologic — —
Subject Hiltonol Other / unclassified — —
Subject Resiquimod Small molecule — —