Impact of Nebulized Dornase Alpha on Mechanically Ventilated Patients

Summary

The investigators hypothesized that dornase alpha, administered twice a day (BID) by in-line nebulizer, would improve oxygenation, compliance, and time to extubation in adult patients receiving mechanical ventilation.

Timeline

Start

2005-11

Primary completion

2006-01

Completion

2006-01

Drugs

Indications