drugset / Trial / NCT01096355

Gamma-Secretase Inhibitor RO4929097 in Treating Patients With Metastatic or Unresectable Solid Malignancies

NCT01096355

Phase 1 Completed 28 enrolled National Cancer Institute (NCI)
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This phase I trial is studying the side effects, best way to give, and best dose of gamma-secretase inhibitor RO4929097 in treating patients with metastatic or unresectable solid malignancies. Enzyme inhibitors, such as gamma-secretase inhibitor RO4929097, may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Timeline

Start
2010-02
Primary completion
2012-07
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject RG4733 Small molecule Oral