Acupuncture in Chronic Migraine: A Randomized Controlled Trial

Completed 68 enrolled Kuang Tien General Hospital

RandomizedParallel-groupOpen-labelTreatment

Summary

The aim of this study was to investigate the efficacy and tolerance of acupuncture treatment compared with pharmacologic treatment in patients with chronic migraines.Besides, the investigators tested whether the clinical effects of acupuncture in chronic migraine prophylaxis are mediated by changes of the plasma CGRP (Calcitonin gene-related peptide).

Timeline

Start: 2008-08
Primary completion: 2010-08
Completion: 2010-08

Publications

Yang CP, Chang MH, Liu PE, Li TC, Hsieh CL, Hwang KL, Chang HH. Acupuncture versus topiramate in chronic migraine prophylaxis: a randomized clinical trial. Cephalalgia. 2011 Nov;31(15):1510-21. doi: 10.1177/0333102411420585. Epub 2011 Oct 21.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Topiramate	Small molecule	100 mg	—

Indications

No indication recorded.