drugset / Trial / NCT01097018

Perifosine Plus Capecitabine Versus Placebo Plus Capecitabine in Patients With Refractory Advanced Colorectal Cancer

NCT01097018

Phase 3 Completed 468 enrolled AEterna Zentaris
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The trial will compare the overall survival of perifosine plus capecitabine to placebo plus capecitabine in patients with refractory advanced colorectal cancer.

Timeline

Start
2010-04
Primary completion
2012-04
Completion
2012-04

Publications

  • Results Results of the X-PECT study: A phase III randomized double-blind, placebo-controlled study of perifosine plus capecitabine (P-CAP) versus placebo plus capecitabine (CAP) in patients (pts) with refractory metastatic colorectal cancer (mCRC). https://meetinglibrary.asco.org/content/98646-114 Abstract Number:LBA3501

Drugs

EvaluationDrugModalityDoseRoute
Comparator Perifosine Small molecule 50 mg
Comparator Capecitabine Small molecule 1000 mg/m2

Indications