drugset / Trial / NCT01097018
Perifosine Plus Capecitabine Versus Placebo Plus Capecitabine in Patients With Refractory Advanced Colorectal Cancer
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The trial will compare the overall survival of perifosine plus capecitabine to placebo plus capecitabine in patients with refractory advanced colorectal cancer.
Timeline
- Start
- 2010-04
- Primary completion
- 2012-04
- Completion
- 2012-04
Publications
- Results Results of the X-PECT study: A phase III randomized double-blind, placebo-controlled study of perifosine plus capecitabine (P-CAP) versus placebo plus capecitabine (CAP) in patients (pts) with refractory metastatic colorectal cancer (mCRC). https://meetinglibrary.asco.org/content/98646-114 Abstract Number:LBA3501
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Perifosine | Small molecule | 50 mg | — |
| Comparator | Capecitabine | Small molecule | 1000 mg/m2 | — |