drugset / Trial / NCT01102218

A Safety Study of Pentoxifylline for the Treatment of Anemia

NCT01102218

Phase 2 Terminated 48 enrolled Fresenius Medical Care North America
RandomizedParallel-groupOpen-labelTreatment

Summary

Chronic kidney disease (CKD) patients have increased levels of inflammation and oxidative stress, which in turn contribute to anemia and cardiovascular disease. Pentoxifylline is known to have anti-inflammatory and anti-oxidant properties, and has shown promise in improving the treatment of patients with anemia. This study will examine the use of pentoxifylline for the treatment of anemia in chronic kidney disease.

Timeline

Start
2010-08
Primary completion
2012-01
Completion
2012-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Pentoxifylline Small molecule 400 mg Oral
Comparator epoetin alfa Protein / enzyme biologic