Vitamin D Supplementation and Acute Respiratory Infection in Older Long-Term Care Residents

Phase 2 Completed 107 enrolled University of Colorado, Denver National Institute on Aging (NIA) · collab The American Geriatrics Society · collab

RandomizedParallel-groupQuadruple-blindPrevention

Summary

This study will test the role of high dose vitamin D supplementation in prevention of acute respiratory infection in older nursing home residents. The investigators hypothesize that residents on high dose vitamin D supplementation will have a lower incidence of acute respiratory infection that those on standard dose vitamin D supplementation.

Timeline

Start: 2010-05
Primary completion: 2014-08
Completion: 2016-07

Publications

Results Ginde AA, Blatchford P, Breese K, Zarrabi L, Linnebur SA, Wallace JI, Schwartz RS. High-Dose Monthly Vitamin D for Prevention of Acute Respiratory Infection in Older Long-Term Care Residents: A Randomized Clinical Trial. J Am Geriatr Soc. 2017 Mar;65(3):496-503. doi: 10.1111/jgs.14679. Epub 2016 Nov 16.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cholecalciferol	Other / unclassified	12000 iu	Oral
Subject	Cholecalciferol	Other / unclassified	100000 iu	Oral

Vitamin D Supplementation and Acute Respiratory Infection in Older Long-Term Care Residents

Summary

Timeline

Publications

Drugs

Indications