Drugs / Cholecalciferol
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Cholecalciferol

Other / unclassified targets NGF, PRODH, VDR via activation

Developed for
vitamin D deficiency · osteoporosis · COVID-19 · type 2 diabetes mellitus · breast cancer · obesity disorder · HIV infectious disease · asthma
+208 more · chronic kidney disease · Crohn disease · end stage renal failure · postmenopausal osteoporosis · prostate cancer · systemic lupus erythematosus · polycystic ovary syndrome · epilepsy · glucose intolerance · heart failure · multiple sclerosis · primary hyperparathyroidism · respiratory tract infectious disorder · sickle cell disease · spinal cord injury · tuberculosis · type 1 diabetes mellitus · cancer · colorectal cancer · common wart · diabetes mellitus · disorders of vitamin D metabolism · gestational diabetes · pneumonia · pregnancy disorder · prostate adenocarcinoma · pulmonary tuberculosis · secondary hyperparathyroidism · acute chest syndrome · acute myeloid leukemia · arterial disorder · bone disorder · brain neoplasm · calcinosis · cardiovascular disorder · chronic obstructive pulmonary disease · depressive disorder · female reproductive system disorder · hepatocellular carcinoma · inflammatory bowel disease · invasive breast carcinoma · leiomyoma · metabolic dysfunction-associated steatohepatitis · nutritional disorder · osteoarthritis, knee · overactive bladder · schizophrenia · traumatic brain injury · ulcerative colitis · acne · acquired hyperprolactinemia · actinic keratosis · acute bronchiolitis · allergic disease · allergic rhinitis · alopecia areata · angioedema · atherosclerosis · atopic eczema · autism · autism spectrum disorder · Barrett esophagus · basal cell carcinoma · beta-thalassemia major · bipolar depression · blood platelet disease · bronchiectasis · bronchiolitis · bronchitis · cardiovascular-kidney-metabolic syndrome · chemotherapy-induced toxicity · childhood onset asthma · chronic granulomatous disease · chronic hepatitis C virus infection · chronic pain syndrome · chronic pancreatitis · chronic urticaria · colon adenoma · colon carcinoma · colorectal adenoma · colorectal neoplasm · Coronaviridae infectious disease · cutaneous melanoma · cystic fibrosis · dengue disease · diabetic kidney disease · diabetic neuropathy · diabetic polyneuropathy · diffuse large B-cell lymphoma · disease of bone structure · disease related to hematopoietic stem cell transplant · Down syndrome · dry eye syndrome · ductal breast carcinoma in situ · eclampsia · endocrine pancreas disorder · enuresis · epicondylitis · estrogen-receptor positive breast cancer · female breast carcinoma · female infertility · gingivitis · glioblastoma · HELLP syndrome · hepatitis C virus infection · hyperbilirubinemia · hyperhomocysteinemia · hyperlipidemia · hyperlipoproteinemia · hypertensive disorder · hypogonadism · idiopathic hypercalciuria · immunodeficiency-related disorder · infectious disease · infectious peritonitis · influenza · iron metabolism disease · leukopenia · lung disorder · malabsorption syndrome · male infertility · malignant pancreatic neoplasm · malposition of teeth with or without hypodontia/oligodontia · melanoma · metabolic bone disorder · metabolic syndrome X · metastasis from malignant tumor of colon · mouth disorder · musculoskeletal system disorder · myocardial infarction · NAFLD1 · nasal disorder · nephrotic syndrome · nervous system disorder · nervous system injury · non-small cell lung carcinoma · optic neuritis · ovarian cancer · pancreatic neoplasm · Parkinson disease · periodontal disorder · periodontitis · peripheral arterial disease · peripheral nerve lesion · peripheral neuropathy · plasma cell myeloma · polymorphic light eruption · post-COVID-19 disorder · psoriasis · rectal cancer · relapsing-remitting multiple sclerosis · respiratory distress syndrome in premature infants · respiratory failure · rheumatoid arthritis · Rotavirus infection · schizoaffective disorder · seasonal affective disorder · secondary hyperparathyroidism of renal origin · skin cancer · statin toxicity · subjective cognitive decline · sudden sensorineural hearing loss · toxic polyneuropathy · triple-negative breast carcinoma · urinary tract infection · urticaria · uterine corpus leiomyoma · vitiligo · acute respiratory distress syndrome · AIDS · Alzheimer disease · anemia · anemia due to chronic disorder · arthropathy · autoimmune thrombocytopenia · B-cell chronic lymphocytic leukemia · benign paroxysmal positional vertigo · cardio-renal syndrome · chronic transplant rejection · cognitive impairment with or without cerebellar ataxia · congestive heart failure · fetal growth restriction · fibromyalgia · Helicobacter pylori infectious disease · inborn error of immunity · infectious disease with sepsis · methicillin-resistant staphylococcus aureus infectious disease · migraine disorder · muscular atrophy · myofascial pain syndrome · myopathy · myositis disease · neonatal sepsis · neurofibromatosis type 1 · neuropathy, painful · obstructive sleep apnea syndrome · overnutrition · peritonitis · plantar wart · prediabetes syndrome · preeclampsia · renal osteodystrophy · restless legs syndrome · seasonal allergic rhinitis · secondary hypoparathyroidism due to impaired parathormon secretion · skin disorder · treatment-refractory schizophrenia · vitamin deficiency disorder
Investigated by
Medical University of South Carolina · Medical University of Graz · National Cancer Institute (NCI) · National Heart, Lung, and Blood Institute (NHLBI) · Organon and Co · University of Tromso
+390 more · Alvogen Korea · Brigham and Women's Hospital · National Institute of Allergy and Infectious Diseases (NIAID) · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) · Ain Shams University · Cairo University · Columbia University · Indonesia University · King Faisal Specialist Hospital & Research Center · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · Case Comprehensive Cancer Center · Emory University · Hanlim Pharm. Co., Ltd. · Hospices Civils de Lyon · Hospital Infantil de Mexico Federico Gomez · Hvidovre University Hospital · Loyola University · MIPO Clinic · Pharmavite LLC · Radboud University Medical Center · Shanghai Jiao Tong University School of Medicine · University Hospital of North Norway · University of Zurich · Zagazig University · Aga Khan University · Andrea Branch · Austrian Science Fund (FWF) · Autoimmunity Centers of Excellence · Baqai Institute of Diabetology and Endocrinology · Canadian Institutes of Health Research (CIHR) · Charite University, Berlin, Germany · Children's Hospital Medical Center, Cincinnati · Children's Hospital of Eastern Ontario · Chuncheon Sacred Heart Hospital · Coordinación de Investigación en Salud, Mexico · Creighton University · Escuela Militar de Graduados de Sanidad, SEDENA · Gary M Brittenham, MD · GlaxoSmithKline · Hartford Hospital · Hospital Regional 1o de Octubre · Johannes Gutenberg University Mainz · Kwang Dong Pharmaceutical co., ltd. · Merck Sharp & Dohme LLC · Ministry of Science and Technology of the People´s Republic of China · National Center for Complementary and Integrative Health (NCCIH) · National Institute on Aging (NIA) · National Institutes of Health (NIH) · National Polytechnic Institute, Mexico · Nîmes University Hospital · Ottawa Hospital Research Institute · Pharma Patent Kft. · Post Graduate Institute of Medical Education and Research, Chandigarh · Roswell Park Cancer Institute · Scotmann Pharmaceuticals · Second Affiliated Hospital of Wenzhou Medical University · Semmelweis University · Seoul National University Hospital · St. Justine's Hospital · Takeda · Tanta University · Thrasher Research Fund · Unity Health Toronto · Universidad Nacional Autonoma de Mexico · University Health Network, Toronto · University Hospital, Angers · University Hospital, Caen · University of Aarhus · University of California, San Francisco · University of Colorado, Denver · University of Liege · University of Minnesota · University of North Carolina, Chapel Hill · all 396 on the full record

Regulatory milestones approvals, filings & regulatory actions · 2 recorded

MilestoneJurisdictionBrandIndicationDateSentence it was read from
Approved EU (EMA) Fosavance 2005-08-24 europa.eu
Approved US (FDA) INFUVITE ADULT 2000-05-18 fda.gov

Trials 357 · started per year

today
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EU approved 2005
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20002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 015 trials
Phase 0 NCT07012161 Feb 2025 → Sep 2026 expected uterine corpus leiomyoma Nahida Akter Recruiting No outcome recorded
Phase 0 NCT05846880 Dec 2024 → May 2028 expected plasma cell myeloma Amany Keruakous, MD, MS. Recruiting No outcome recorded
Phase 0 NCT06053281 Jan → Dec 2024 epilepsy DINA KEUMALA SARI Unknown No outcome recorded
Phase 0 NCT06539260 Jan 2023 → Jul 2024 immune system disorder, nervous system disorder Suzhou Municipal Hospital of Anhui Province Completed No outcome recorded
Phase 0 NCT05208827 Jan 2022 → Jan 2025 gestational diabetes, nutritional disorder Women's Hospital School Of Medicine Zhejiang University Unknown No outcome recorded
Phase 0 NCT05142072 Dec 2021 → Jan 2022 nasal disorder Deraya University Completed No outcome recorded
Phase 0 NCT04772196 Dec 2020 → Dec 2026 expected Prisma Health-Midlands Active not recruiting No outcome recorded
Phase 0 NCT04134065 Dec 2019 → Oct 2020 Crohn disease, vitamin D deficiency Nanjing University School of Medicine Unknown No outcome recorded
Phase 0 NCT03028519 Jan 2017 → Dec 2020 ovarian cancer University of Oklahoma Completed No outcome recorded
Phase 0 NCT02936999 Aug 2016 → Jan 2019 female breast carcinoma Inova Health Care Services Terminated No outcome recorded
Phase 123 trials
Phase 1 NCT07068282 Jul 2024 → Jan 2025 COVID-19 King Faisal Specialist Hospital & Research Center Completed No outcome recorded
Phase 1 NCT05389943 Jun → Aug 2022 vitamin D deficiency University of Sargodha Unknown No outcome recorded
Phase 1 NCT06209229 May 2022 → May 2023 non-small cell lung carcinoma MIPO Clinic Completed No outcome recorded
Phase 1 NCT04844164 Apr 2019 → May 2021 ACTH-dependent Cushing syndrome, acromegaly, primary hyperparathyroidism, type 1 diabetes mellitus Endocrinology Research Centre, Moscow Completed No outcome recorded
Phase 1 NCT03824171 Feb → Mar 2019 osteoporosis Addpharma Inc. Completed No outcome recorded
Phase 1 NCT04120064 Jan 2019 → Dec 2020 vitamin D deficiency Parkview Medical Center Terminated No outcome recorded
Phase 1 NCT03759262 Dec 2018 → May 2020 disease related to hematopoietic stem cell transplant Children's Hospital Los Angeles Completed No outcome recorded
Phase 1 NCT03467789 Oct 2018 → Jan 2023 basal cell carcinoma, nevoid basal cell carcinoma syndrome Case Comprehensive Cancer Center Completed No outcome recorded
Phase 1 NCT03270709 Apr → Oct 2018 HIV infectious disease, vitamin D deficiency Emory University Terminated No outcome recorded
Phase 1 NCT03321318 Jul → Sep 2017 Alvogen Korea Unknown No outcome recorded
Phase 1/211 trials
Phase 1/2 NCT04244474 Sep → Dec 2019 pneumonia, vitamin D deficiency Cairo University Unknown No outcome recorded
Phase 1/2 NCT05149339 Mar 2019 → Feb 2020 acute myeloid leukemia, vitamin D deficiency Zagazig University Completed No outcome recorded
Phase 1/2 NCT02856503 Jan 2019 → Jan 2023 ductal breast carcinoma in situ, invasive breast carcinoma Eli Avisar, MD Withdrawn No outcome recorded
Phase 1/2 NCT03037593 Jun 2017 → Jun 2020 gestational diabetes University of Minnesota Withdrawn No outcome recorded
Phase 1/2 NCT02099955 Jan 2012 → Dec 2015 spinal cord injury, vitamin D deficiency James J. Peters Veterans Affairs Medical Center Completed No outcome recorded
Phase 1/2 NCT01181193 Mar 2011 → Mar 2013 glioblastoma Soroka University Medical Center Unknown No outcome recorded
Phase 1/2 NCT01276587 Jan → Jun 2011 sickle cell disease Gary M Brittenham, MD Completed No outcome recorded
Phase 1/2 NCT01375010 Jan 2011 → Feb 2016 HIV infectious disease Columbia University Completed No outcome recorded
Phase 1/2 NCT01769625 Jan 2009 → Nov 2016 breast cancer Hartford Hospital Completed No outcome recorded
Phase 1/2 NCT01425476 Jul 2008 → Nov 2016 breast cancer Hartford Hospital Completed No outcome recorded
Phase 283 trials
Phase 2 NCT07647198 Aug 2026 → Aug 2029 expected leiomyoma Sheikh Shakhbout Medical City Recruiting No outcome recorded
Phase 2 NCT07269457 Mar 2026 → Dec 2028 expected traumatic brain injury Lagos State University Recruiting No outcome recorded
Phase 2 NCT06757244 Feb 2025 → Feb 2028 expected pancreatic neoplasm Hopital Foch Recruiting No outcome recorded
Phase 2 NCT06570200 Oct 2024 → Oct 2025 overdue periodontitis Cairo University Not yet recruiting No outcome recorded
Phase 2 NCT06508099 May 2024 → May 2026 overdue acute biphenotypic leukemia, chronic myeloid leukemia, lymphoblastic lymphoma, myelodysplastic syndrome St. Petersburg State Pavlov Medical University Recruiting No outcome recorded
Phase 2 NCT06101147 Sep 2023 → Apr 2024 polycystic ovary syndrome, vitamin D deficiency Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh Completed No outcome recorded
Phase 2 NCT06071481 Jun → Dec 2023 dengue disease Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh Unknown No outcome recorded
Phase 2 NCT05269017 Jun 2022 → Mar 2023 Menoufia University Unknown No outcome recorded
Phase 2 NCT05077813 Dec 2021 → Feb 2022 tuberculosis Kafrelsheikh University Unknown No outcome recorded
Phase 2 NCT04677816 Oct 2021 → Aug 2026 overdue invasive breast carcinoma, triple-negative breast carcinoma, vitamin D deficiency Wake Forest University Health Sciences Recruiting No outcome recorded
Phase 2/318 trials
Phase 2/3 NCT05795933 Apr 2023 → Jun 2024 bronchiolitis Sohag University Completed No outcome recorded
Phase 2/3 NCT05523609 Nov 2022 → Sep 2024 breast cancer Tanta University Unknown No outcome recorded
Phase 2/3 NCT06054919 Apr 2021 → Nov 2023 vitamin D deficiency Indonesia University Unknown No outcome recorded
Phase 2/3 NCT03984890 Aug 2019 → Dec 2021 chronic granulomatous disease Children's Hospital of Fudan University Completed No outcome recorded
Phase 2/3 NCT03602430 Jul → Sep 2018 calcinosis, vitamin D deficiency Ain Shams University Completed No outcome recorded
Phase 2/3 NCT04411901 Mar → Sep 2018 bronchiectasis Heba Omara Completed No outcome recorded
Phase 2/3 NCT02868827 Aug 2017 → Nov 2019 vitamin D deficiency King Abdullah Medical City Terminated No outcome recorded
Phase 2/3 NCT02881957 Oct 2016 → Oct 2018 brain aneurysm, brain neoplasm, epilepsy, intracerebral hemorrhage +4 University of Utah Completed No outcome recorded
Phase 2/3 NCT02143505 Mar 2014 → Feb 2017 colorectal adenoma Shanghai Jiao Tong University School of Medicine Unknown No outcome recorded
Phase 2/3 NCT07671547 Jan 2014 → Dec 2015 breast cancer, chemotherapy-induced toxicity, leukopenia MIPO Clinic Completed No outcome recorded
Phase 367 trials
Phase 3 NCT07598032 Jun 2026 → Jun 2028 expected prostate adenocarcinoma University of Ilorin Teaching Hospital Not yet recruiting No outcome recorded
Phase 3 NCT03516968 Dec 2023 → Mar 2027 expected obesity disorder Hospices Civils de Lyon Recruiting No outcome recorded
Phase 3 NCT05613192 Oct 2022 → Mar 2023 NAFLD1 Ain Shams University Unknown No outcome recorded
Phase 3 NCT04991324 Sep 2022 → Sep 2024 inflammatory bowel disease University Hospital, Basel, Switzerland Completed No outcome recorded
Phase 3 NCT05417880 Aug 2022 → Feb 2023 type 2 diabetes mellitus Scotmann Pharmaceuticals Unknown No outcome recorded
Phase 3 NCT05270343 Jun 2022 → Jan 2023 type 1 diabetes mellitus Shanghai Jiao Tong University School of Medicine Unknown No outcome recorded
Phase 3 NCT05425914 Nov 2021 → Mar 2022 dry eye syndrome, vitamin D deficiency University of Faisalabad Completed No outcome recorded
Phase 3 NCT05326841 Oct 2021 → Jan 2022 systemic lupus erythematosus Dr Cipto Mangunkusumo General Hospital Completed No outcome recorded
Phase 3 NCT04780061 Jul 2021 → May 2022 COVID-19 The Canadian College of Naturopathic Medicine Terminated No outcome recorded
Phase 3 NCT04775381 Jun 2021 → Dec 2025 overdue Hôpital NOVO Recruiting No outcome recorded
Phase 455 trials
Phase 4 NCT07006714 Sep 2025 → Jul 2027 expected osteoarthritis, vitamin D deficiency University of Miami Active not recruiting No outcome recorded
Phase 4 NCT05758259 Feb → Aug 2023 acne Indonesia University Unknown No outcome recorded
Phase 4 NCT05657678 Dec 2022 → Jan 2026 vitamin D deficiency Uniwersytecki Szpital Kliniczny w Opolu Unknown No outcome recorded
Phase 4 NCT07673497 Sep 2022 → Mar 2023 inflammatory bowel disease, iron metabolism disease, vitamin D deficiency Gazi University Completed No outcome recorded
Phase 4 NCT05276960 Jun 2022 → Aug 2024 cystic fibrosis, osteoporosis, vitamin D deficiency Hospital Infantil de Mexico Federico Gomez Completed No outcome recorded
Phase 4 NCT04952857 Aug → Nov 2021 COVID-19 Post Graduate Institute of Medical Education and Research, Chandigarh Completed No outcome recorded
Phase 4 NCT04739592 Jul 2021 → Jul 2023 osteoarthritis, knee Peking Union Medical College Hospital Unknown No outcome recorded
Phase 4 NCT05216419 Jun 2021 → Oct 2024 vitamin D deficiency Seoul National University Hospital Completed No outcome recorded
Phase 4 NCT04629534 May → Dec 2021 vitamin D deficiency Medical University of South Carolina Terminated No outcome recorded
Phase 4 NCT05591170 Apr → Aug 2021 vitamin D deficiency Department of Endocrinology, Centre of Postgraduate Medical Education Completed No outcome recorded
Phase not applicable85 trials
NCT06201013 Apr → Sep 2026 expected overactive bladder Children's Hospital of Chongqing Medical University Recruiting No outcome recorded
NCT07053657 Sep → Dec 2025 overdue cardiovascular-kidney-metabolic syndrome Anhui Medical University Recruiting No outcome recorded
NCT07269223 Sep → Dec 2025 overdue ulcerative colitis University of Veterinary and Animal Sciences, Lahore - Pakistan Recruiting No outcome recorded
NCT07455656 Aug 2025 → Aug 2026 overdue malposition of teeth with or without hypodontia/oligodontia Al-Azhar University Recruiting No outcome recorded
NCT07115342 Aug → Oct 2025 overdue allergic rhinitis Tanta University Recruiting No outcome recorded
NCT07553052 Jun → Aug 2025 HIV infectious disease Universitas Sebelas Maret Completed No outcome recorded
NCT07045883 Jun 2025 → Jun 2026 overdue sudden sensorineural hearing loss Zhongshan Hospital Xiamen University Active not recruiting No outcome recorded
NCT07167797 Jan → May 2025 Rotavirus infection University of Baghdad Completed No outcome recorded
NCT06508333 Dec 2024 → Mar 2025 enuresis Xing Liu Completed No outcome recorded
NCT06139133 Jan 2024 → Dec 2025 gestational diabetes IIMC, Riphah International University, Pakistan Unknown No outcome recorded
Also used as a comparator or background therapy in 208 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 02 trials
Phase 0 NCT06073925 Comparator Dec 2023 → Jul 2024 autoimmune thrombocytopenia Mansoura University Unknown No outcome recorded
Phase 0 NCT02337257 Comparator Apr 2014 → Sep 2015 periodontitis, vitamin D deficiency Augusta University Unknown No outcome recorded
Phase 115 trials
Phase 1 NCT06515548 Comparator Aug 2024 → Feb 2025 Cairo University Completed No outcome recorded
Phase 1 NCT06565728 Comparator Nov 2022 → May 2023 fetal growth restriction Cairo University Completed No outcome recorded
Phase 1 NCT05739786 Comparator May → Nov 2022 common wart Combined Military Hospital Abbottabad Completed No outcome recorded
Phase 1 NCT02698293 Background Dec 2019 → Jan 2023 anus disorder, in situ carcinoma Abramson Cancer Center at Penn Medicine Withdrawn No outcome recorded
Phase 1 NCT03475719 Comparator Jan → Feb 2018 postmenopausal osteoporosis Huons Co., Ltd. Unknown No outcome recorded
Phase 1/27 trials
Phase 1/2 NCT06301178 Comparator Feb 2024 → Feb 2025 skin disorder Mostafa Bahaa Completed No outcome recorded
Phase 1/2 NCT04489628 Comparator Aug 2020 → Jun 2021 COVID-19 University Hospitals Cleveland Medical Center Withdrawn No outcome recorded
Phase 1/2 NCT04591600 Background Jul → Sep 2020 COVID-19 Alkarkh Health Directorate-Baghdad Completed No outcome recorded
Phase 1/2 NCT03406897 Comparator Jul 2018 → Jul 2024 hypoglycemia, type 1 diabetes mellitus Rodolfo Alejandro Completed No outcome recorded
Phase 1/2 NCT03101150 Comparator Oct 2012 → Oct 2014 preeclampsia, vitamin D deficiency King Fahad Medical City Completed No outcome recorded
Phase 238 trials
Phase 2 NCT06596122 Comparator Oct 2024 → Nov 2026 expected neuropathy, painful Abdelrahman Mahmoud Not yet recruiting No outcome recorded
Phase 2 NCT05578404 Comparator Oct 2022 → Apr 2023 NAFLD1 Tanta University Completed No outcome recorded
Phase 2 NCT05104970 Comparator Aug 2022 → Jan 2023 vitamin D deficiency Scotmann Pharmaceuticals Unknown No outcome recorded
Phase 2 NCT04067726 Background Aug 2019 → Sep 2025 overdue female breast upper-inner quadrant cancer Washington University School of Medicine Active not recruiting No outcome recorded
Phase 2 NCT04011930 Comparator Mar 2019 → Feb 2020 chronic obstructive pulmonary disease Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh Unknown No outcome recorded
Phase 2/310 trials
Phase 2/3 NCT05922696 Comparator May → Sep 2022 anemia, vitamin D deficiency Ain Shams University Completed No outcome recorded
Phase 2/3 NCT05460338 Comparator May → Sep 2022 vitamin D deficiency Ain Shams University Completed No outcome recorded
Phase 2/3 NCT04145492 Comparator Sep 2019 → Jan 2020 end stage renal failure Ain Shams University Unknown No outcome recorded
Phase 2/3 NCT03911843 Background Jan 2017 → Dec 2018 type 1 diabetes mellitus Azienda Ospedaliero Universitaria Maggiore della Carita Completed No outcome recorded
Phase 2/3 NCT02738619 Comparator Mar → Dec 2016 allergic disease Hospital General de Mexico Unknown No outcome recorded
Phase 339 trials
Phase 3 NCT07448974 Comparator May 2026 → Mar 2030 expected prediabetes syndrome, type 2 diabetes mellitus Tufts Medical Center Not yet recruiting No outcome recorded
Phase 3 NCT07229456 Comparator Oct 2024 → Oct 2025 overdue Ain Shams University Active not recruiting No outcome recorded
Phase 3 NCT06690723 Comparator Jun 2022 → Sep 2024 obstructive sleep apnea syndrome University Malaysia Sarawak Completed No outcome recorded
Phase 3 NCT05305183 Background May 2022 → May 2023 osteoporosis Shandong New Time Pharmaceutical Co., LTD Unknown No outcome recorded
Phase 3 NCT04883203 Comparator Apr → Sep 2020 COVID-19 University of Monastir Completed No outcome recorded
Phase 455 trials
Phase 4 NCT07510568 Comparator Jun 2026 → Dec 2027 expected HELLP syndrome, eclampsia St Mary's Hospital, Lacor Not yet recruiting No outcome recorded
Phase 4 NCT07448844 Comparator Feb → May 2026 overdue common wart, plantar wart Riphah International University Recruiting No outcome recorded
Phase 4 NCT07196670 Comparator Sep → Dec 2025 overdue plantar wart Cairo University Not yet recruiting No outcome recorded
Phase 4 NCT06551337 Comparator Apr 2024 → Dec 2026 expected bronchiectasis Queen Mary Hospital, Hong Kong Recruiting No outcome recorded
Phase 4 NCT05884372 Comparator Aug 2023 → Jul 2025 postmenopausal osteoporosis Xi'an Honghui Hospital Completed No outcome recorded
Phase not applicable42 trials
NCT07460336 Background May 2026 → Dec 2027 expected latent autoimmune diabetes in adults Second Xiangya Hospital of Central South University Not yet recruiting No outcome recorded
NCT07597096 Comparator May → Jun 2026 overdue secondary hypoparathyroidism due to impaired parathormon secretion King Edward Medical University Not yet recruiting No outcome recorded
NCT06861062 Comparator Apr 2025 → Dec 2030 expected type 2 diabetes mellitus Huazhong University of Science and Technology Recruiting No outcome recorded
NCT06553729 Comparator Feb 2025 → Dec 2026 expected glucose intolerance Huazhong University of Science and Technology Recruiting No outcome recorded
NCT06736093 Comparator Jan 2025 → May 2026 overdue Institute of Liver and Biliary Sciences, India Recruiting No outcome recorded

Press releases naming this drug 1 release

DateIssuerRelease
2013-05-31 Daiichi Sankyo Daiichi Sankyo Launches Denotas® Chewable Combination Tablets with Calcium/Natural Vitamin D3/Magnesium daiichisankyo.com

Evidence & citations 45 cited values

Every value below carries the sentence it was read from. 584 sources stand behind the page.

FieldValueCited text
Known as cholecalciferol “The investigators hypothesise that supplementation of vitamin D3 (Cholecalciferol), in addition to standard antibiotic and other supportive therapy in the management of...” NCT02185196
322

“Genotype 1 or 4 HCV-infected patients with null response to previous PegIFN/RBV treatment and with hypovitaminosis D (< 30 ng/mL) prospectively received cholecalciferol 100000...” PMID 25987791 May 2015

“Neonates were given vitamin D3 (cholecalciferol) in an oral drops formulation (400 IU/drop), at a dose of 400 IU once a day until the serum bilirubin level was out of...” NCT07098234

“Participants with deficient levels of vitamin D will receive vitamin D supplementation at the initiation of chemotherapy with 50,000 IU of oral vitamin D3 (cholecalciferol)...” NCT04677816

“A new fixed-dose combination (FDC) formulation of raloxifene 60 mg and cholecalciferol 800 IU was developed to improve the medication compliance and overall efficacy of...” PMID 36247744 Sep 2022

“To investigate the effect of cholecalciferol (vitamin D3) supplementation on peripheral immune cell frequency and N-glycan branching in patients with relapsing-remitting...” PMID 32830462 Aug 2020

“vitamin D will be obtained from a commercial product in the Egyptian pharmacies called (Devarol S) in the form of injectable ampoules containing 200000 IU of cholecalciferol (2.5 mg/ml)” NCT06570200

“vitamin D3 (Cholecalciferol), vitamin D3 obtained from 2 ml vials containing 200,000 IU each (Devarol- S- 200.000 I.U. produced by Memphis. for Pharmaceutical and Chemical Industries)” NCT04244474

“Deficient volunteers (Vit-D serum <30 ng/mL) were assigned (V1) to receive either 100,000 IU/15 days of cholecalciferol (D, n = 19), or a placebo (P, n = 19), over a 3 month period.” PMID 30800121 Feb 2019

“The patients received oral liquid cholecalciferol supplementation (OsteVit DTM, Key Pharmaceuticals, Macquarie Park, NSW, Australia), supplied in 50 mL bottles (5000 units in 1 mL).” NCT04134065

“will receive supplementary Vitamin D3(NIVAGEN Vitamin D3 Cholecalciferol 50000 IU) oral once weekly for 3 months as adjuvant therapy in combination with their treatment for ITP.” NCT06073925

“Subjects receive Vitamin D supplementation (cholecalciferol 100,000 IU, drinking solution, 2 mL vial) at a rate of 1 drinking vial of 100,000 IU cholecalciferol every month.” NCT01409694

“We investigated the effect of the nutrient vitamin D (cholecalciferol), a biochemical precursor of calcitriol, on PSA levels and the rate of rise of PSA in these patients.” PMID 15749627 2005

“25-hydroxyvitamin D (cholecalciferol, \[25(OH)D\]) levels \<30 ng/ml will be treated with vitD (20,000 IU/wk) or placebo in a 2:1 randomized controlled trial over 24 weeks” NCT01721915

“Vitamin D3 (cholecalciferol), the most powerful form of vitamin D, is synthesized in the skin from 7-dehydrocholesterol by action of sunlight (ultraviolet B radiation).” NCT01500005

“high-dose oral vitamin D3 (VD3; cholecalciferol) combined with photodynamic therapy (PDT) can improve the clearance of squamous precancers (actinic keratoses [AKs]).” PMID 35314199 Mar 2022

“Patients in the routine calcium group received oral supplements of 1,500 mg/day elemental calcium (by calcium carbonate) and 1,000 IU/day cholecalciferol for 2 weeks” NCT03484416

“The participants were randomized to 1 of 3 daily treatments: (1) 0.5-1.0 µg calcitriol and 1200 IU (30 µg) cholecalciferol, (2) 1200 IU cholecalciferol, (3) placebo.” PMID 22592096 May 2012

“National guidelines recommend the administration of 800 IU cholecalciferol daily for an effective treatment, especially during the winter (poor sun exposition).” NCT03141593

“Will receive oral cholecalciferol (vitamin D3) in a single daily dose of 800 IU from the time of diagnosis of sepsis until discharge from the NICU” NCT02273843

“patients with recent onset T1D received one dose of allogenic ASC (1 × 106 cells/kg) and cholecalciferol 2,000 UI/day for 6 months (group 1).” PMID 33939911 Apr 2021

“Subjects received 50,000 IU every 4 to 5 weeks (n = 11) or 100,000 IU every 6 to 8 weeks (n = 32) of oral cholecalciferol for 1 year.” PMID 35045559 Jan 2022

“The clinical-scientific hypothesis of this study is that replacement of vitamin D (cholecalciferol) will improve the symptoms of RLS.” NCT03063190

“Patients were randomized 1:1 to receive oral cholecalciferol 100 000 IU (n = 163) or placebo (n = 153) every 2 weeks for 24 months.” PMID 40063041 Apr 2025

“This intervention consists of oral Vitamin D3 (cholecalciferol) capsules administered every two weeks to improve vitamin D status.” NCT07269223

“Determination of the effect of cholecalciferol (VitD3) (2200 IU/day) on metabolic parameters in patients with metabolic syndrome.” NCT01237769

“vitamin D3 (cholecalciferol) supplementation will benefit Veteran subjects diagnosed with early-stage, low-risk prostate cancer” NCT01759771

“Participants were randomly assigned to either the topical vitamin D group (cholecalciferol 50 mcg) or the topical placebo group” PMID 39372262 Oct 2024

“A single 1.5 mL dose containing 150,000 IU cholecalciferol (100,000 IU/mL) administered on Day 1 (Solution in Olive Oil B.P. )” NCT03257215

Cholecalciferol(Vitamin D) Intramuscular injection of 600,000 units of Cholecalciferol for 2 doses given at week 0 and week 4” NCT05002530

Cholecalciferol(Vitamin D) Intramuscular injection of 600,000 units of Cholecalciferol for 2 doses given at week 0 and week 4” NCT05077813

“Patients with SLE (n = 267) were randomized 2:1 to receive either oral cholecalciferol 2000 IU/day or placebo for 12 months.” PMID 23204220 Dec 2012

Cholecalciferol (Vitamin D) is a fat-soluble vitamin that is involved in maintaining the serum calcium-phosphorus gradient.” NCT05166005

“Each tablet contained 500 milligrams of calcium carbonate and 200 international units (IU) of vitamin D3(cholecalciferol).” NCT04618952

“The drug being tested is called VigantOL® oil - a very effective form of Vitamin D hormone supplement (cholecalciferol).” NCT01285401

“vitamin D3 (an aqueous preparation of cholecalciferol (Devarol® ampoule 200 000 IU/2 ml, Memphis, Egypt) (2.5 mg/ ml)” NCT06327581

“risedronate 150mg and cholecalciferol 30,000 IU 1 tablet + Placebo(for risedronate 150mg) 1 tablet by once a month.” NCT01806792

“once weekly 70mg oral dose of alendronate co-formulated with 5600IU vitamin D3 (cholecalciferol) for 24 weeks.” NCT01968850

“oral cholecalciferol 50,000 U weekly for 8 weeks followed by 10,000 U weekly for 44 weeks or matching placebo” PMID 34656640 Oct 2021

“Vitamin D supplement (cholecalciferol) up to 4000 IU/day to reach blood levels of 60-80 ng/ml of 25(OH)D.” NCT02786875

“randomized into 3 vitamin D3 (cholecalciferol) treatment arms: 50,000 IU/wk; 5000 IU/d; and 1000 IU/d.” PMID 26707619 Dec 2015

“It is prepared by using Cholecalciferol 2ml ampoule (200.000 I.U.) within topical oral gel formulation.” NCT04308161

“Vitamin D3 (cholecalciferol) will be given to the study group Ia orally 50000 IU weekly for 6 weeks.” NCT04529668

Cholecalciferol supplementation was fixed at 1000 IU/day (25 mcg/day), both in cases and controls.” NCT03911843

cholecalciferol 5,000 IU once/week and cholecalciferol 40,000 IU once/week orally for 24 weeks” NCT04377399

“AIM: Effect of high dose, oral cholecalciferol supplementation on SARS-CoV-2 viral clearance.” PMID 33184146 Nov 2020

“The interventional drug, 2,00,000 IU Vitamin D3 oral solution in the form of cholecalciferolNCT06071481

“The tablets contain the vitamin D in the form of vitamin D3, also known as cholecalciferol.” NCT01695460

“The aqueous solution of vitamin D3 (cholecalciferol) will be used ampoule 200,000 IU/2 ML,” NCT05324904

“Combination tablet of Cholecalciferol (800 IU or 20 ug) and calcium carbonate (500 mg)” NCT02922803

“oral cholecalciferol supplementation of 250,000 IU during their next CF clinic visit” NCT02613884

“Ascorbic Acid 100 mg/day Cholecalciferol 400 IU/day Dl-Alpha Tocopheryl Acetate 11IU” NCT02620345

Cholecalciferol 4000 units orally daily Calcium carbonate 500 mg orally twice daily” NCT00736632

“Patients will receive a cholecalciferol supplementation added to a fruit juice.” NCT04775381

Cholecalciferol (vitamin D3 \[D3\]) is the main dietary source of vitamin D” NCT03783273

“Vitamin D3 (cholecalciferol) will be provided to participants of the study.” NCT02996721

“Film-coated tablet Biodal 50,000 IU containing cholecalciferol 50,000 IU” NCT02328404

“One capsule containing (cholecalciferol 400 IU) was taken every day .” NCT04319289

“Pills of: 10μg cholecalciferol (Vitamin D)once daily during 9 months” NCT01101698

“either oral cholecalciferol at 25,000 IU/wk or placebo for 3 months” PMID 29504254 Mar 2018

“Vitamin D3 or D2 (Cholecalciferol or Ergocalciferol respectively)” NCT03405207

“100,000 IU Vitamin D3 (cholecalciferol) monthly for 12 months.” NCT01102374

“4000 IU Vitamin D3 (cholecalciferol) daily = 40 drops daily” NCT03101150

“<Ibandronate 150mg + cholecalciferol(Vitamin D3) 24,000IU>” NCT01581320

“Bazedoxifene acetate 22.6mg, Cholecalciferol 8.0mg(=800IU)” NCT03475719

“Daily vitamin D (cholecalciferol) tablets and rocaltrol” NCT00497900

“200,000 IU / 1 mL of Cholecalciferol (1 ml) Oral form” NCT04883203

Cholecalciferol (Vitamin D3) and Calcitriol Treatment” NCT00459563

“150 mg of ibandronate + 24,000 IU of cholecalciferolNCT05266261

“the dietary form of Vitamin D (cholecalciferol, D3)” NCT03467789

cholecalciferol (vitamin D3) 2000 IU capsules daily” NCT02925195

Cholecalciferol 400 IU orally every day for 6 weeks” NCT01337635

“100000 IU Cholecalciferol Intramuscular every month” NCT04010942

“Vitamin D3 (cholecalciferol), 2000 IU per day.” NCT01704859

“Vitamin D3 (cholecalciferol), 2000 IU per day.” NCT01684722

“Vitamin D3 (cholecalciferol), 2000 IU per day.” NCT01169259

“Vitamin D3 (cholecalciferol), 2000 IU per day.” NCT04573946

Cholecalciferol 50000 IU once monthly orally” NCT00677339

“either cholecalciferol 50,000 IU or placebo” NCT04489628

Cholecalciferol 200000 IU insta ampoule” NCT05104970

“Vitamin D3 tablets (cholecalciferol)” NCT01741181

“vitamin D3 1000 IU (Cholecalciferol)” NCT03783338

“400 IU Vitamin D3 (cholecalciferol)” NCT00412074

“Dietary Supplement: cholecalciferolNCT01198548

“800-6000 IU cholecalciferol per day” NCT01182870

“Dietary Supplement: CholecalciferolNCT00887432

“Drug: Vitamin D3 (Cholecalciferol)” NCT00956839

Cholecalciferol granule 10 mg” NCT03005340

“Vitamin D3 (Cholecalciferol)” NCT06757244

“Vitamin D3 (Cholecalciferol)” NCT07269457

“Vitamin D3 (Cholecalciferol)” NCT04442412

“Vitamin D3 (Cholecalciferol)” NCT06690723

“Vitamin D3 (cholecalciferol)” NCT01574027

“Vitamin D (Cholecalciferol )” NCT07167797

“Vitamin D3 cholecalciferolNCT03101319

“24,000 IU cholecalciferolNCT04991324

cholecalciferol 200,000IU” NCT03233295

cholecalciferolNCT05733117

NCT00285467

NCT02002000

NCT02783924

NCT05364567

NCT01480869

NCT04917458

NCT03602430

NCT01388855

NCT01892748

NCT00729651

NCT02698293

NCT01390480

NCT00507000

NCT05431218

NCT01675297

NCT03321318

NCT03759262

NCT02208310

NCT03234244

NCT02726113

NCT02750293

NCT02337257

NCT00419068

NCT02005718

NCT05578404

NCT02074631

NCT04502667

NCT05591170

NCT03320915

NCT00685594

NCT01052181

NCT04411901

NCT00610688

NCT04733625

NCT01884844

NCT00421343

NCT01477801

NCT00418587

NCT00473239

NCT05430087

NCT04399746

NCT01385345

NCT04216459

NCT03691896

NCT01580007

NCT03406897

NCT04179461

NCT03880734

NCT02096133

NCT02234544

NCT01904110

NCT01384539

NCT02217553

NCT01769625

NCT00366470

NCT01632514

NCT05270343

NCT01265615

NCT00682214

NCT00976339

NCT00798993

NCT01395290

NCT03648528

NCT01046773

NCT00288873

NCT05613192

NCT05276960

NCT00982722

NCT04952857

NCT01728987

NCT05460338

NCT00243256

NCT01304927

NCT02443246

NCT00491920

NCT01431430

NCT06585995

NCT03038516

NCT01130181

NCT01466465

NCT01130311

NCT01765010

NCT04535791

NCT01911169

NCT02197286

NCT03188796

NCT05149339

NCT00893451

NCT01689779

NCT07597096

NCT01532349

NCT01325311

NCT01974245

NCT02537509

NCT01559974

NCT01656070

NCT00674154

NCT01400009

NCT06054919

NCT05922696

NCT06053281

NCT03824171

NCT01190683

NCT00752401

NCT00809744

NCT02737423

NCT00412087

NCT01092338

NCT02069990

NCT06596122

NCT01967459

NCT03588884

NCT02341495

NCT07673497

NCT03382314

NCT07068282

NCT01138475

NCT03615833

NCT02238418

NCT02975492

NCT00400491

NCT06419712

NCT02654093

NCT02186106

NCT00859651

NCT04552951

NCT02186015

NCT03070483

NCT03504280

NCT01968590

NCT01312714

NCT01214928

NCT01528176

NCT04011930

NCT05860270

NCT00292591

NCT05347082

NCT03920397

NCT02507843

NCT06508242

NCT01248442

NCT01601847

NCT02598635

NCT00677534

NCT01175798

NCT02185222

NCT07510568

NCT01141998

NCT01019642

NCT07448974

NCT02881957

NCT04476511

NCT05216419

NCT01736865

NCT01173848

NCT07229456

NCT05386784

NCT01292720

NCT04652544

NCT00812578

NCT01022398

NCT01240512

NCT01170494

NCT01037140

NCT01447355

NCT06301178

NCT04115982

NCT04847947

NCT00427037

NCT05080530

NCT01608451

NCT01636570

NCT02936999

NCT00968877

NCT02031692

NCT01412710

NCT01698476

NCT04844164

NCT00692913

NCT03799406

NCT04840238

NCT04636086

NCT01425476

NCT01166165

NCT03742505

NCT04120064

NCT01518959

NCT01222234

NCT01024777

NCT02868827

NCT01074216

NCT01637155

NCT05880030

NCT03264625

NCT00960232

NCT01955577

NCT02890823

NCT02092376

NCT02178488

NCT02661191

NCT01538485

NCT00004488

NCT02416193

NCT00992797

NCT04629534

NCT01702974

NCT00092066

NCT01419119

NCT01419262

NCT03284294

NCT02092701

NCT04145492

NCT00641771

NCT04793529

NCT04344041

NCT00004489

NCT03781895

NCT03516968

NCT01436916

NCT05372224

NCT00133640

NCT04621500

NCT03475225

NCT00092079

NCT04262934

Known as 1,25 dihydroxycholecalciferol 1,25 dihydroxycholecalciferol (vitamin D3) is the most active hormonal form of vitamin D.” NCT07455656
Known as 1,25 Dihydroxyvitamin D3 “Effects of Vitamin D3 (1,25 Dihydroxyvitamin D3) on Pharmacokinetics and Absorption of Folic Acid and Fexofenadine in Healthy Volunteers” NCT01856348
Known as 25-Hydroxyvitamin D “Cholecalciferol (25-Hydroxyvitamin D)” NCT00798993
Known as 25OH vitamin D3 ClinicalTrials.gov intervention name — accepted as the source's own label NCT01588795
1

NCT00889629

Known as A11CC05 Colecalciferol A11CC05 ColecalciferolNCT01748370
1

A11CC05 ColecalciferolNCT01721915

Known as BABY D3 “Vitamin D3 as "BABY D3"” NCT01287455
Known as cholecalciferol (vitamin D) cholecalciferol (vitamin D)NCT01769625
1

cholecalciferol (Vitamin D)NCT01425476

Known as cholecalciferol (vitamin D3) cholecalciferol (vitamin D3)NCT02172651
Known as Colecalciferol “Vitamin D3 (cholecalciferol, colecalciferol) is one of type of vitamin D which is made by the skin when exposed to sunlight; it is also found in some foods and can be taken as...” NCT01472445
16

“Alendronic acid 70mg with Colecalciferol 70mcg” NCT03006003

“30,000 IU vitamin D (colecalciferol)” NCT04840238

Colecalciferol 16.800 IU per week” NCT02122627

“Vitamin D3 ( Colecalciferol)” NCT01264874

“Vitamin D3 ( Colecalciferol)” NCT06690723

“A11CC05 ColecalciferolNCT01748370

NCT00306410

NCT00504946

NCT02958501

NCT07012161

NCT02393482

NCT01339676

NCT01432704

NCT00397475

NCT02419105

NCT01075022

Known as Colecalciferol, cholecalciferol, vitamin D3 Colecalciferol, cholecalciferol, vitamin D3NCT02122627
Known as d-alpha tocopherol “Oral LPCN 1144 + d-alpha tocopherol total daily dose of 450 mg testosterone undecanoate + 476 mg d-alpha tocopherol administered as 225 mg testosterone undecanoate + 238 mg...” NCT04134091
Known as Dekristol “Once weekly treatment with peroral colecalciferol capsules (Dekristol®, Swiss-Caps, Switzerland) containing 20 mg of colecalciferol corresponding to 20000 IU or 0.5 mg of vitamin D” NCT01339676
Known as Devarol “vitamin D3 (an aqueous preparation of cholecalciferol (Devarol® ampoule 200 000 IU/2 ml, Memphis, Egypt)” NCT06327581
Known as Devarol S “The aqueous solution of vitamin D3 is used (Devarol S 200,000IU/2ml ) 0.6 ml (60,000 IU ) will be slowly injected into the base of the largest wart” NCT07196670
Known as Devarol- S- 200.000 I.U. “vitamin D3 (Cholecalciferol), vitamin D3 obtained from 2 ml vials containing 200,000 IU each (Devarol- S- 200.000 I.U. produced by Memphis. for Pharmaceutical and Chemical Industries)” NCT04244474
Known as IM vitamin D3 - Inj Arachitol (Solvay, India) IM vitamin D3 - Inj Arachitol (Solvay, India)NCT00956839
Known as inactive vitamin D “Cholecalciferol (inactive vitamin D)” NCT04145492
Known as Juvit D3 ClinicalTrials.gov intervention name — accepted as the source's own label NCT04768023
Known as Maintenance Vitamin D ClinicalTrials.gov intervention name — accepted as the source's own label NCT05846880
Known as Naderin ClinicalTrials.gov intervention name — accepted as the source's own label NCT07671508
1

NCT07671547

Known as Native Vitamin D ClinicalTrials.gov intervention name — accepted as the source's own label NCT05884372
Known as NIVAGEN Vitamin D3 “will receive supplementary Vitamin D3(NIVAGEN Vitamin D3 Cholecalciferol 50000 IU) oral once weekly for 3 months as adjuvant therapy in combination with their treatment for ITP.” NCT06073925
Known as Oral vitamin D3 - Tab Cipcal (Cipla, India) Oral vitamin D3 - Tab Cipcal (Cipla, India)NCT00956839
Known as OsteVit DTM “The patients received oral liquid cholecalciferol supplementation (OsteVit DTM, Key Pharmaceuticals, Macquarie Park, NSW, Australia), supplied in 50 mL bottles (5000 units in 1 mL).” NCT04134065