drugset / Trial / NCT03270709
Effect of High-Dose Vitamin D3 in Smokers and Non-Smokers With and Without HIV
Non-randomizedParallel-groupOpen-labelTreatment
Summary
Supplementation with vitamin D improves HIV+ macrophages phagocytosis in vitro. There is evidence to suggest that administering vitamin D can in fact improve immune function in individuals. The study will evaluate the impact of high dose vitamin D in HIV+ smokers' and HIV- smokers' in vivo. The primary goal is to improve innate immune host response to infection in patients already at high risk by virtue of HIV and smoking status.
Timeline
- Start
- 2018-04-11
- Primary completion
- 2018-10-15
- Completion
- 2018-10-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cholecalciferol | Other / unclassified | 450000 iu | Oral |