drugset / Trial / NCT03270709

Effect of High-Dose Vitamin D3 in Smokers and Non-Smokers With and Without HIV

NCT03270709

Phase 1 Terminated 7 enrolled Emory University
Non-randomizedParallel-groupOpen-labelTreatment

Summary

Supplementation with vitamin D improves HIV+ macrophages phagocytosis in vitro. There is evidence to suggest that administering vitamin D can in fact improve immune function in individuals. The study will evaluate the impact of high dose vitamin D in HIV+ smokers' and HIV- smokers' in vivo. The primary goal is to improve innate immune host response to infection in patients already at high risk by virtue of HIV and smoking status.

Timeline

Start
2018-04-11
Primary completion
2018-10-15
Completion
2018-10-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Cholecalciferol Other / unclassified 450000 iu Oral