drugset / Trial / NCT02099955

Vitamin D Deficiency and Replacement on Pulmonary and Endocrine Function in SCI

NCT02099955

Phase 1/2 Completed 88 enrolled James J. Peters Veterans Affairs Medical Center
Non-randomizedSingle-groupOpen-labelTreatment

Summary

Studies have shown that individuals who have suffered a spinal cord injury are at an increased risk of Vitamin D deficiency compared to able-bodied individuals. It has recently been shown that Vitamin D deficiency is linked to a large number of diseases and conditions, including chronic lung disease, vascular problems, and insulin resistance. If this common nutritional deficiency is proven to be the cause of some of these diseases and conditions in persons with SCI, then it may easily be remedied with a cheap and effective therapeutic approach: vitamin D replacement therapy. Because of the high prevalence of vitamin D deficiency in persons with SCI, this therapy alone or in combination with other treatment options will be expected to significantly improve overall well being in the SCI population, decrease hospitalization rate, and the lower the financial burden of care.

Timeline

Start
2012-01
Primary completion
2015-12
Completion
2016-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Cholecalciferol Other / unclassified 2000 iu
Subject Cholecalciferol Other / unclassified 4000 iu