Pilot Trial to Evaluate the Effect of Vitamin D on Melanocyte Biomarkers

Summary

The purpose of this study is to determine the signaling pathways and changes in gene expression in melanocytes of subjects with a history of non-melanoma skin cancer who are exposed to oral vitamin D. If vitamin D is found to inhibit a signaling pathway involved in the development of melanoma such as BRAF, a protein involved in cell proliferation, then oral vitamin D could be explored further as a chemoprevention for melanoma skin cancer.

Timeline

Start

2012-09

Primary completion

2014-05

Completion

2014-05

Drugs

Indications