Vitamin D Supplementation in Individuals With a Chronic Spinal Cord Injury

Summary

The main objective of this placebo-controlled randomized double-blinded study is to investigate the effect of vitamin D supplementation on vitamin D status (25(OH)D concentration in the blood) among individuals with a chronic spinal cord injury (SCI). Further, the effects of vitamin D supplementation on several other parameters (e.g. bone density and mood) are investigated, which could reveal positive secondary effects of supplementation that are especially relevant for clinical practice.

Timeline

Start

2021-05-19

Primary completion

2024-01-23

Completion

2024-01-23

Publications

• Hertig-Godeschalk A, Flueck JL, Scheel-Sailer A, Perret C, Brinkhof MWG. No discernible effect of vitamin D supplementation on secondary outcomes in chronic spinal cord injury: Findings from a randomized controlled trial. J Spinal Cord Med. 2025 Oct 1:1-12. doi: 10.1080/10790268.2025.2557078. Online ahead of print.
• Hertig-Godeschalk A, Brinkhof MWG, Scheel-Sailer A, Perret C, Jenny A, Landmann G, Wyss PO, Flueck JL. Vitamin D supplementation in chronic spinal cord injury (VitD-SCI): study protocol for a randomised controlled trial. BMJ Open. 2021 Dec 17;11(12):e053951. doi: 10.1136/bmjopen-2021-053951.

Drugs

Indications