drugset / Trial / NCT02066688
Study of Folic Acid, Calcium and Vitamin D in Preventing Colorectal Polyps and Colorectal Cancer
Phase 2/3
Unknown
2400 enrolled
Shanghai Jiao Tong University School of Medicine
Ministry of Science and Technology of the People´s Republic of China · collab
RandomizedFactorialQuadruple-blindPrevention
Summary
Folic acid (FA) and its derivatives (folate) which play a role in nucleotide synthesis and methylation reactions as well as calcium and vitamin D are assumed to be effective in the prevention of colorectal polyps and Colorectal cancer (CRC). The aim of this study is to investigate the roles of FA as well as calcium and vitamin D in the prevention of CRC.
Timeline
- Start
- 2013-01
- Primary completion
- 2015-12
- Completion
- 2017-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Calcium carbonate | Other / unclassified | 1200 mg | Oral |
| Subject | Cholecalciferol | Other / unclassified | 250 iu | Oral |
| Subject | folic acid | Other / unclassified | 1 mg | Oral |