drugset / Trial / NCT01465113

Vitamin D Supplementation on 15-Prostaglandin Dehydrogenase Expression in Barrett's Esophagus

NCT01465113

Phase 0 Completed 26 enrolled Case Comprehensive Cancer Center
Non-randomizedParallel-groupOpen-labelPrevention

Summary

This study is being conducted to determine if vitamin D supplementation increases the level of a protein that may be involved in decreasing the risk of esophageal cancer in patients with Barrett's esophagus. Subjects with Barrett's esophagus will take vitamin D supplementation for 2-12 weeks depending on the severity of their condition, and receive an upper endoscopy procedure before and after vitamin D supplementation trial.

Timeline

Start
2010-05
Primary completion
2016-02
Completion
2016-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Cholecalciferol Other / unclassified 50000 iu Oral
Subject Metformin Small molecule 2000 mg
Background Omeprazole Other / unclassified 20 mg Oral

Indications