drugset / Trial / NCT03588767

Endocrine Response of the Organism to Polytrauma

NCT03588767

Completed 60 enrolled University Hospital Ostrava
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The serious injury causes a complex acute response of the organism to the injury in affected patients, which is manifested in the neuroendocrine, immune and metabolic areas, with an often persisting catabolic state, with a subsequent negative impact upon bone metabolism. By a timely administration of the D3 vitamin and an anabolic, we attempt to achieve an earlier activation of the anabolic phase of patient resuscitation after serious trauma regarding the monitoring of laboratory values of bone metabolism.

Timeline

Start
2017-05-31
Primary completion
2020-05-30
Completion
2021-01-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Cholecalciferol Other / unclassified 5000 iu Intramuscular
Subject Nandrolone Decanoate Small molecule 50 mg Intramuscular

Indications