drugset / Trial / NCT02856503
Effect of High Dose Vitamin D on Cancer Biomarkers and Breast Cancer Tumors
Non-randomizedParallel-groupOpen-labelTreatment
Summary
High-doses of Vitamin D (VD) may be used as targeted therapy against breast cancer. The investigators will assess the effect of high dose VD on the following biomarkers in the breast cancer cells: VDR, estrogen receptor (ER), progesterone receptor (PR), epidermal growth factor receptor 2 (Her2/neu), androgen receptor (AR), as well as epidermal growth factor receptor 1 (EGFR) and Ki-67, as markers of proliferation, and E-cadherin, a marker of invasion and metastasis.
Timeline
- Start
- 2019-01-13
- Primary completion
- 2023-01-31
- Completion
- 2024-04-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cholecalciferol | Other / unclassified | 50000 iu | Oral |