drugset / Trial / NCT02172651

Vitamin D in Patients With Stage I-III Colon Cancer or Resectable Colon Cancer Liver Metastases

NCT02172651

RandomizedSingle-groupTriple-blindBasic science

Summary

This study seeks to learn more about the vitamin D receptor and its relationship to colon cancer. The Vitamin D receptor is found in colon cancer cells. When Vitamin D binds to the receptor in the cancer cells, it may stop cancer cells from growing abnormally and may cause cancer cell death. Vitamin D has been used in other research studies and information from those other research studies suggests that Vitamin D may help in the treatment of colon cancer. Participants will receive either high-dose vitamin D or standard-dose vitamin D. The study drug will be given 14-28 days prior to your surgery. The number of days will depend on when the surgery is scheduled.

Timeline

Start
2014-07-14
Primary completion
2027-04-15
Completion
2027-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Cholecalciferol Other / unclassified 10000 iu Oral