drugset / Trial / NCT01102608

Neoadyuvant High-dose of Ifosfamide and Concurrent Radiotherapy in Soft Tissue Sarcoma

NCT01102608

Phase 2 Completed 32 enrolled Spanish Group for Research in Sarcomas
NaSingle-groupOpen-labelTreatment

Summary

To study the activity and toxicity of a neoadjuvant regimen including high-dose ifosfamide in combination with radiotherapy, and subsequent surgery, in high-risk soft tissue sarcomas.

Timeline

Start
2008-03
Primary completion
2011-10
Completion
2011-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Ifosfamide Small molecule 12000 mg/m2 Intravenous
Background 2-MERCAPTOETHANESULFONIC ACID Small molecule 6000 mg/m2 Intravenous

Indications