drugset / Trial / NCT01109888

Administration of Increased Dose of GnRH Antagonist for Coasting for Decreasing the Risk for Ovarian Hyperstimulation Syndrome( OHSS)

NCT01109888 ↗

Phase 1/2 Withdrawn Wolfson Medical Center

Summary

Coasting is one of the means to reduce the risk of OHSS for patients at risk for severe OHSS. During coasting gonadotrophin administration is withheld until serum E2 levels drop to a range considered safe. Prolonged coasting reduces the chance for implantation and pregnancy. The aim of the study is to explore whether an increased dose of GnRH Antagonist will shorten the coasting period without an adverse effect on cycle outcome.

Timeline

Start
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Primary completion
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Completion
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Outcome

Outcome not reported

Stopped (Enrollment): “there was no percipitant enrolled”

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cetrorelix Other / unclassified 0.25 mg —
Comparator Cetrorelix Other / unclassified 0.5 mg —