drugset / Trial / NCT01110616
EEG (Electroencephalogram) Platform Standardization in Healthy Male Subjects (3134-010)
RandomizedCrossoverDouble-blindTreatment
Summary
The objective of this study is to test the experimental reproducibility and within-subject variability of qEEG (quantitative electroencephalogram) using two probe compounds: MK3134 and lorazepam. This study will test the hypothesis that EEG (Electroencephalogram) theta power, averaged across a topographical region of interest is decreased 6 hours after administration of MK3134 compared to placebo. The objective of this study is to test the experimental reproducibility and within-subject variability of qEEG using two probe compounds: MK3134 and lorazepam.
Timeline
- Start
- 2010-06
- Primary completion
- 2010-10
- Completion
- 2010-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lorazepam | Small molecule | 2 mg | Oral |
| Subject | MK3134 | Unknown | 25 mg | Oral |