drugset / Trial / NCT01115049
Hexetidine and Chlorobutanol for Lesions Due to Prostheses
RandomizedParallel-groupTriple-blindSupportive care
Summary
Objectives: The study aimed at assessing the efficacy of a new mouthwash in treating oral lesions due to removable prostheses. Methods: The present prospective randomized clinical trial was performed on 44 patients. The experimentation lasted for 4 weeks and 4 operators participated. The effects of the mouthwash were evaluated subjectively and objectively, with questionnaires, Visual Analogic Scales and clinical examinations. The results were statistically analyzed. The following variables were recorded: presence of mucosal lesions due to incongruous removable prostheses and lasting of pain after rinsing.
Timeline
- Start
- 2010-02
- Primary completion
- 2010-03
- Completion
- 2010-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Chlorhexidine | Small molecule | 0.2 % | — |
| Subject | chlorobutanol | Small molecule | 0.5 % | — |
| Subject | hexetidine | Small molecule | 0.1 % | — |