Metformin and Folate in Pregnant Polycystic Ovary Syndrome(PCOS) Women

Summary

A more recent prospective nonrandomized placebo-controlled double-blind clinical study demonstrated that metformin exerts a slight but significant deleterious effect on serum homocysteine (Hcy) levels in patients with PCOS, and supplementation with folate is useful to increase the beneficial effect of metformin on the vascular endothelium.

Timeline

Start

2010-03

Primary completion

2011-05

Completion

2011-05

Drugs

Indications