drugset / Trial / NCT01127880

Role of Antibiotics to Reduce Infectious Complications in Tube Thoracotomy Management of Traumatic Hemopneumothorax

NCT01127880

Phase 2/3 Completed 50 enrolled St. Luke's Hospital, Pennsylvania
RandomizedParallel-groupQuadruple-blindPrevention

Summary

The purpose of this study is to examine the efficacy of prophylactic antibiotics in patients with chest tubes for management of thoracic injuries in the reduction of the incidence of empyema as compared to placebo.

Timeline

Start
2005-07
Primary completion
2009-12
Completion
2009-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Cefazolin Small molecule 1 g
Comparator Clindamycin Unknown 300 mg

Indications