drugset / Trial / NCT01131182
Study of Sitagliptin Treatment in Patients With Type 2 Diabetes During Ramadan (0431-263)
RandomizedParallel-groupOpen-labelTreatment
Summary
This study will examine whether the incidence of hypoglycemia in patients fasting for Ramadan is lower when treated with sitagliptin as compared to sulfonylurea treatment.
Timeline
- Start
- 2010-06-13
- Primary completion
- 2010-11-04
- Completion
- 2010-11-04
Publications
- Results Al Sifri S, Basiounny A, Echtay A, Al Omari M, Harman-Boehm I, Kaddaha G, Al Tayeb K, Mahfouz AS, Al Elq A, Radican L, Ozesen C, Katzeff HL, Musser BJ, Suryawanshi S, Girman CJ, Davies MJ, Engel SS; 2010 Ramadan Study Group. The incidence of hypoglycaemia in Muslim patients with type 2 diabetes treated with sitagliptin or a sulphonylurea during Ramadan: a randomised trial. Int J Clin Pract. 2011 Nov;65(11):1132-40. doi: 10.1111/j.1742-1241.2011.02797.x. Epub 2011 Sep 27.
- Lee SWH, Chen WS, Sellappans R, Md Sharif SB, Metzendorf MI, Lai NM. Interventions for people with type 2 diabetes mellitus fasting during Ramadan. Cochrane Database Syst Rev. 2023 Jul 12;7(7):CD013178. doi: 10.1002/14651858.CD013178.pub2.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Gliclazide | Small molecule | — | Oral |
| Comparator | Glimepiride | Small molecule | — | Oral |
| Comparator | Glyburide | Small molecule | — | Oral |
| Subject | Sitagliptin | Small molecule | 100 mg | Oral |
| Background | Metformin | Small molecule | — | — |