drugset / Trial / NCT01134341

Pralatrexate and Bexarotene in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma

NCT01134341

Phase 1 Completed 34 enrolled Acrotech Biopharma Inc.
NaSingle-groupOpen-labelTreatment

Summary

This study is designed to determine the recommended dose, safety, pharmacokinetics, and early efficacy of the combination of pralatrexate plus oral bexarotene in patients with relapsed or refractory CTCL.

Timeline

Start
2010-03
Primary completion
2015-08
Completion
2015-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Bexarotene Small molecule 150 mg Oral
Subject Bexarotene Small molecule 300 mg Oral
Subject Pralatrexate Other / unclassified 10 mg/m2 Intravenous
Subject Pralatrexate Other / unclassified 15 mg/m2 Intravenous