drugset / Trial / NCT01136408

A Dose Response Study of Dabigatran Etexilate(BIBR 1048) in Pharmacodynamics and Safety in Patients With Non-valvular Atrial Fibrillation in Comparison to Warfarin

NCT01136408

Phase 2 Completed 174 enrolled Boehringer Ingelheim
RandomizedParallel-groupOpen-labelPrevention

Summary

The primary objective was to evaluate the safety of dabigatran etexilate(BIBR 1048) administered orally at doses of 110 and 150 mg, twice daily, for 12 weeks in patients with non-valvular atrial fibrillation (paroxysmal, persistent or permanent) in comparison with warfarin.

Timeline

Start
2005-11
Primary completion
2006-09
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Dabigatran etexilate Unknown 110 mg Oral
Subject Dabigatran etexilate Unknown 150 mg Oral
Comparator Warfarin Small molecule

Indications