drugset / Trial / NCT01145183
Pharmacogenetics of Doxazosin for Cocaine Dependence
Phase 2
Completed
96 enrolled
Baylor College of Medicine
National Institute on Drug Abuse (NIDA) · collab
RandomizedParallel-groupQuadruple-blindDiagnostic
Summary
Doxazosin, an alpha 1-adrenergic receptor antagonist, may play an important role in cocaine addiction in humans. This study will evaluate to what extent the prospective screening for catecholamine related polymorphisms for alpha 1 NE receptor/transporter, COMT and DBH as main targets predict the treatment efficacy of doxazosin for cocaine-using behavior.
Timeline
- Start
- 2010-03
- Primary completion
- 2015-09
- Completion
- 2015-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Doxazosin | Small molecule | 8 mg | — |