drugset / Trial / NCT01146795

Neoadjuvant Therapy for Ovarian Cancer

NCT01146795 ↗

Phase 2 Completed 32 enrolled Jason D. Wright Genentech, Inc. · collab
NaSingle-groupOpen-labelTreatment

Summary

This study is to determine the feasibility of administering neoadjuvant carboplatin, paclitaxel, and bevacizumab without excessive dose modification or cycle delay in patients with epithelial ovarian cancer, primary peritoneal cancer or fallopian tube cancer. This study will also investigate the rate of optimal cytoreduction, response rate and progression free and overall survival, and to assess the quality of life for patients with epithelial ovarian cancer, primary peritoneal cancer or fallopian tube cancer treated with neoadjuvant carboplatin, paclitaxel and bevacizumab.

Timeline

Start
2010-05-17
Primary completion
2015-04-13
Completion
2015-04-13

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 15 mg/kg —
Subject Carboplatin Small molecule — —
Subject Paclitaxel Small molecule 175 mg/m2 —