drugset / Trial / NCT01146795
Neoadjuvant Therapy for Ovarian Cancer
NaSingle-groupOpen-labelTreatment
Summary
This study is to determine the feasibility of administering neoadjuvant carboplatin, paclitaxel, and bevacizumab without excessive dose modification or cycle delay in patients with epithelial ovarian cancer, primary peritoneal cancer or fallopian tube cancer. This study will also investigate the rate of optimal cytoreduction, response rate and progression free and overall survival, and to assess the quality of life for patients with epithelial ovarian cancer, primary peritoneal cancer or fallopian tube cancer treated with neoadjuvant carboplatin, paclitaxel and bevacizumab.
Timeline
- Start
- 2010-05-17
- Primary completion
- 2015-04-13
- Completion
- 2015-04-13
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bevacizumab | Monoclonal antibody | 15 mg/kg | — |
| Subject | Carboplatin | Small molecule | — | — |
| Subject | Paclitaxel | Small molecule | 175 mg/m2 | — |