Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery
Summary
The purpose of the study is to determine the opiate sparing effects of intravenously administered dexamethasone in outpatient knee surgery. Dexamethasone is a glucocorticoid with well known antiemetic effects. However, the analgesic effects of dexamethasone have not been adequately researched. Following surgery, patients are typically discharged home with PO opiates to manage post-operative pain. The investigators believe that by using VAS (Visual Analog Scale) for Pain the investigators can show that a single dose of dexamethasone can reduce pain scales and opiate consumption post-operatively, on Post Operative Day (POD 1) when compared to placebo.
Timeline
- Start
- 2009-12
- Primary completion
- 2012-12
- Completion
- 2012-12
Outcome
Outcome not reported
Stopped: “investigators changed jobs, no longer affiliated with institution”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexamethasone | Small molecule | 8 mg | Intravenous |
Indications
No indication recorded.