drugset / Trial / NCT01159496
Multiple Ascending Dose Study To Assess Safety, Tolerability And Pharmacokinetics Of PF-05212377 (SAM-760)
RandomizedSingle-groupDouble-blind
Summary
This is a multiple ascending dose study to assess the safety, tolerability and pharmacokinetics of PF-05212377 (SAM-760) administered orally once a day for 14 days to healthy young adults and healthy elderly subjects. The study will be conducted under double-blind conditions (neither the investigator nor the subject will know if he/she has received PF-05212377 or a placebo). The Sponsor will know if the subject has received active treatment or a placebo.
Timeline
- Start
- 2010-07
- Primary completion
- 2010-12
- Completion
- 2010-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PF-05212377 | Small molecule | 1.5 mg | Oral |
| Subject | PF-05212377 | Small molecule | 5 mg | Oral |
| Subject | PF-05212377 | Small molecule | 15 mg | Oral |
| Subject | PF-05212377 | Small molecule | 30 mg | Oral |
| Subject | PF-05212377 | Small molecule | 50 mg | Oral |
Indications
No indication recorded.