Evaluating the Efficacy and Safety of Fluticasone Furoate Inhalation Powder in the Treatment of Asthma in Adults and Adolescents

Summary

A randomised, double-blind, double-dummy, placebo controlled (with rescue medication), multicenter study to evaluate the efficacy and safety of Fluticasone Furoate inhalation powder in the treatment of persistent asthma in adults and adolescents.

Timeline

Start

2010-06-30

Primary completion

2012-01-01

Completion

2012-01-16

Outcome

Met primary endpoint

registry analysis (superiority or other test); Placebo vs FF 100 µg OD; p = 0.009; Mean Difference (Final Values) 0.146 (95% CI 0.036 to 0.257); ANCOVA NCT01159912 ↗

Publications

• O'Byrne PM, Jacques L, Goldfrad C, Kwon N, Perrio M, Yates LJ, Busse WW. Integrated safety and efficacy analysis of once-daily fluticasone furoate for the treatment of asthma. Respir Res. 2016 Nov 24;17(1):157. doi: 10.1186/s12931-016-0473-x.

Drugs

Indications