drugset / Trial / NCT01160354
Plerixafor and Clofarabine in Frontline Treatment of Elderly Patients With Acute Myelogenous Leukemia (AML)
NaSingle-groupOpen-labelTreatment
Summary
The goal of Part 1 of this clinical research study is to learn about the safety of the combination of plerixafor and clofarabine when given to patients with previously untreated AML who are at least 60 years old. The goal of Part 2 of this study is to learn if the combination of plerixafor and clofarabine can help to control previously untreated AML in patients who are at least 60 years old. Study was closed early and did not progress to Part 2.
Timeline
- Start
- 2010-08
- Primary completion
- 2016-03
- Completion
- 2016-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Clofarabine | Other / unclassified | 20 mg/m2 | Intravenous |
| Subject | Plerixafor | Small molecule | 240 ug/kg | Subcutaneous |
| Subject | Plerixafor | Small molecule | 320 ug/kg | Subcutaneous |
| Subject | Plerixafor | Small molecule | 400 ug/kg | Subcutaneous |