drugset / Trial / NCT01160354

Plerixafor and Clofarabine in Frontline Treatment of Elderly Patients With Acute Myelogenous Leukemia (AML)

NCT01160354

NaSingle-groupOpen-labelTreatment

Summary

The goal of Part 1 of this clinical research study is to learn about the safety of the combination of plerixafor and clofarabine when given to patients with previously untreated AML who are at least 60 years old. The goal of Part 2 of this study is to learn if the combination of plerixafor and clofarabine can help to control previously untreated AML in patients who are at least 60 years old. Study was closed early and did not progress to Part 2.

Timeline

Start
2010-08
Primary completion
2016-03
Completion
2016-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Clofarabine Other / unclassified 20 mg/m2 Intravenous
Subject Plerixafor Small molecule 240 ug/kg Subcutaneous
Subject Plerixafor Small molecule 320 ug/kg Subcutaneous
Subject Plerixafor Small molecule 400 ug/kg Subcutaneous